Pregnancy-associated cancers: a population-based study
https://doi.org/10.18027/2224-5057-2023-13-1-5-10
Abstract
Introduction: Pregnancy-associated cancers are malignant neoplasms (MNs) diagnosed during pregnancy or within 12 months after delivery. The study aimed to evaluate the prevalence of pregnancy-associated cancers at the population level.
Materials and methods: The population database was created from databases of two regional systems: the automated system Pregnancy Monitoring Program and the ONCOR system.
Results: Overall, 357 female patients with pregnancy-associated cancers were identified. The incidence rate was 1.659 per 1,000 pregnancies. The most common MN localizations were cervix, breast, thyroid, and ovary. Most female patients were between 45 and 49 years of age. Stage IV breast cancer was identified in a large proportion of women undergoing delivery. Conversely, cervical and ovarian cancers were commonly diagnosed at early stages. The 1-year survival rate of patients with pregnancy-associated cancers was higher than in the entire cancer population.
Conclusions: Pregnancy-associated cancers are still a complex and poorly understood issue that requires additional studies, disease-specific monitoring and treatment protocols.
About the Authors
V. V. Petkau
Sverdlovsk Regional Oncological Dispensary; Ural State Medical University
Russian Federation
Russian Federation
Vladislav V. Petkau, MD, PhD, Deputy Chief Physician for Drug Treatment; associate professor, Department of Oncology and Imaging
Ekaterinburg
K. E. Kiselyova
Sverdlovsk Regional Oncological Dispensary
Russian Federation
Russian Federation
Ksenia Ye. Kiseleva, physician trainee
Ekaterinburg
E. A. Kiselev
Sverdlovsk Regional Oncological Dispensary
Russian Federation
Russian Federation
Evgeny A. Kiselev, MD, PhD, Deputy Chief Physician for Clinical Care
Ekaterinburg
S. A. Efremov
Business computer LLC
Russian Federation
Russian Federation
Sergei A. Efremov, Director
Ekaterinburg
N. O. Ankudinov
Regional Children»s Clinical Hospital
Russian Federation
Russian Federation
Nikolai O. Ankudinov, Head of the Remote Obstetric Consultative Center, Yekaterinburg Clinical Perinatal Center
Ekaterinburg
A. A. Karimova
Ural State Medical University
Russian Federation
Russian Federation
Alisa A. Karimova, Candidate of Pharmaceutical Sciences, associate professor, Department of Public Health and Healthcare
Ekaterinburg
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Review
For citations:
Petkau V. ., Kiselyova K.E., Kiselev E.A., Efremov S. ., Ankudinov N.O., Karimova A.A. Pregnancy-associated cancers: a population-based study. Malignant tumours. 2023;13(1):5-10. (In Russ.) https://doi.org/10.18027/2224-5057-2023-13-1-5-10
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