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РЕЦЕПТОРЫ ФАКТОРА РОСТА ФИБРОБЛАСТОВ ПРИ ЗЛОКАЧЕСТВЕННЫХ ОПУХОЛЯХ

https://doi.org/10.18027/2224-5057-2014-4-19-34

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Аннотация

Одними из наиболее исследуемых в настоящее время в онкологии маркеров являются рецепторы к фактору роста фибробластов, а также лиганды к нему. В данном обзоре мы сконцентрируемся на молекулярных процессах, возникающих при активации рецепторов к фактору роста фибробластов. А также рассмотрим, с какой частотой встречаются нарушения экспрессии компонентов сигнального пути данного рецептора при различных онкологических заболеваниях.

Об авторах

М. Ю. Федянин
Российский онкологический научный центр им. Н. Н. Блохина
Россия

Контактная информация: Федянин Михаил Юрьевич — к.м.н., врач-онколог отделения клинической фармакологии и химиотерапии ФГБУ «Российский онкологический научный центр им. Н. Н. Блохина». Россия, г. Москва, Каширское шоссе 24, fedianinmu@mail.ru



Д. Н. Хмелькова
Центр живых систем, МФТИ, г. Долгопрудный
Россия

Хмелькова Дарья Николаевна — н.с. лаборатории трансляционных исследований и персонализированной медицины Центра живых систем, МФТИ, Россия, Московская область, г. Долгопрудный, Институтский пер., darya.khmelkova@gmail.com



Т. С. Серебрийская
Центр живых систем, МФТИ, г. Долгопрудный
Россия

Серебрийская Татьяна Сауловна — к.б.н., с.н.с. лаборатории трансляционных исследований и персонализированной медицины Центра живых систем, МФТИ, Россия, Московская область, г. Долгопрудный, Институтский пер., ts.serebriyskaya@gmail.com



Т. А. Никольская
Центр живых систем, МФТИ, г. Долгопрудный
Россия

Никольская Татьяна Анатольевна — к.б.н., заведующая лабораторией трансляционных исследований и персонализированной медицины Центра живых систем, МФТИ, Россия, Московская область, г. Долгопрудный, Институтский пер.



С. А. Тюляндин
Российский онкологический научный центр им. Н. Н. Блохина
Россия

Тюляндин Сергей Алексеевич — д.м.н., профессор, заведующий отделением клинической фармакологии и химиотерапии ФГБУ «Российский онкологический научный центр им. Н. Н. Блохина». Россия, г. Москва, Каширское шоссе 24, stjulandin@mail.ru



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Для цитирования:


Федянин М.Ю., Хмелькова Д.Н., Серебрийская Т.С., Никольская Т.А., Тюляндин С.А. РЕЦЕПТОРЫ ФАКТОРА РОСТА ФИБРОБЛАСТОВ ПРИ ЗЛОКАЧЕСТВЕННЫХ ОПУХОЛЯХ. Злокачественные опухоли. 2014;(4):19-34. https://doi.org/10.18027/2224-5057-2014-4-19-34

For citation:


Fedyanin M.Y., Hmel’kova D.N., Serebriyskaya T.S., Nikol’skaya T.A., Tyulyandin S.A. Fibroblast growth factor receptors in malignant tumors. Malignant tumours. 2014;(4):19-34. (In Russ.) https://doi.org/10.18027/2224-5057-2014-4-19-34

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