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Breast implant capsule‑associated squamous cell carcinoma: case report

https://doi.org/10.18027/2224-5057-2020-10-4-30-37

Abstract

Breast augmentation with the use of silicone breast implants is a routine practice for breast surgeons. Breast implant capsule‑associated squamous cell carcinoma is a rare and aggressive malignant tumor accounting for less than 0,1 % of invasive breast cancer. Currently there is no single concept of a complex therapy for such tumors due to the low incidence rate. The article describes a case of a 49‑year‑old female patient after surgical treatment of left‑sided breast implant capsule‑associated squamous cell carcinoma diagnosed in 2019. After the disease progression the patient underwent removal of the chest wall tumor with resection of ribs 3–5, allo‑and autoplasty, and left axillary lymph node dissection (ALND). In most cases, breast implant capsule‑associated squamous cell carcinoma is treated surgically but the role of adjuvant chemotherapy, radiation therapy, and endocrine therapy is still ambiguous.

About the Authors

A.  D. Zikiryakhodzhaev
P. Hertzen Moscow Oncology Research Institute — Branch of the National Medical Research Radiological Centre
Russian Federation

Azizzhon D. Zakiryakhodzhaev, Head of the Department of Oncology and Breast and Skin Reconstructive Plastic Surgery

Moscow



Sh.  G. Khakimova
P. Hertzen Moscow Oncology Research Institute — Branch of the National Medical Research Radiological Centre; Tashkent Pediatric Medical Institute
Uzbekistan

Shakhnoz. G. Khakimova, MD, PhD, Department of Breast and Skin Reconstructive Plastic Surgery

 Moscow, Tashkent



E.  A. Rasskazova
P. Hertzen Moscow Oncology Research Institute — Branch of the National Medical Research Radiological Centre
Russian Federation

Elena A. Rasskazova, MD, PhD, Researcher of the Department of Oncology and Breast and Skin Reconstructive Plastic Surgery

Moscow



E.  K. Saribekyan
P. Hertzen Moscow Oncology Research Institute — Branch of the National Medical Research Radiological Centre
Russian Federation

Erik K. Saribekyan, MD, PhD, DSc, Leading Researcher of the Department of Oncology and Breast and Skin Reconstructive 
Plastic Surgery

Moscow



D.  F. Omarova
P. Hertzen Moscow Oncology Research Institute — Branch of the National Medical Research Radiological Centre
Russian Federation

Dzhanet F. Omarova, Postgraduate Student, of the Department of Oncology and Breast and Skin Reconstructive Plastic 
Surgery

Moscow



V.  S. Surkova
P. Hertzen Moscow Oncology Research Institute — Branch of the National Medical Research Radiological Centre
Russian Federation

Victoria S. Surkova, Pathologist, Department of Pathological Anatomy

Moscow



G.  G. Khakimova
Tashkent Pediatric Medical Institute; Republican specialized Scientific and practical Medical Center of Oncology and Radiology
Uzbekistan

Gulnoz G. Khakimova, MD, PhD, oncologist

Tashkent



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Review

For citations:


Zikiryakhodzhaev A.D., Khakimova Sh. ., Rasskazova E.A., Saribekyan E.K., Omarova D.F., Surkova V.S., Khakimova G.G. Breast implant capsule‑associated squamous cell carcinoma: case report. Malignant tumours. 2020;10(4):30-37. (In Russ.) https://doi.org/10.18027/2224-5057-2020-10-4-30-37

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ISSN 2224-5057 (Print)
ISSN 2587-6813 (Online)