Preview

Malignant tumours

Advanced search

Metastasis of gastric adenocarcinoma in the endometrium and the cervix. Сlinical case

https://doi.org/10.18027/2224-5057-2018-8-1-66-70

Abstract

Comprehensive approach and a highly qualified morphological analysis are important conditions for timely diagnosis and development of tactics of pathogenetic treatment of cancer patients. This clinical case demonstrates a multimodal approach to the differential diagnosis of metastatic cancer. Due to oncological alertness, the clinical data, qualitative morphological study and close cooperation of all participants in a multidisciplinary group a metastasis of the gastric signet-ring cell carcinoma was diagnosed in the cervix, allowing to optimize treatment of the patient.

About the Authors

A. E. Protasova
Saint Petersburg State University; OOO «AVA-PETER»; North-Western State Medical University named after I. I. Mechnikov; Almazov National Medical Research Centre
Russian Federation

MD, Dsc Med, Professor of the Department of Oncology

Professor of the Department of Oncology

Professor of the Department of Obstetrics and Gynecology

Head of the Center of Oncology



I. V. Semenova
OOO «AVA-PETER»
Russian Federation
obstetrician-gynecologist


G. A. Raskin
Saint Petersburg State University; Russian Scientific Center for Radiology and Surgical Technologies named after Academician A. M. Granov
Russian Federation

MD, DSc Med, Head of the Department of Pathological Anatomy

Professor of the Department of Oncology



M. S. Mukhina
Russian Scientific Center for Radiology and Surgical Technologies named after Academician A. M. Granov
Russian Federation
MD PhD Med, Senior Researcher


N. S. Kuzmina
OOO «AVA-PETER»
Russian Federation
Head of the Gynecological Department


R. V. Orlova
Saint Petersburg State University; L. G. Sokolov Memorial Hospital № 122
Russian Federation

MD, DSc Med, Professor, Head of the Department of Oncology

Head of the Specialized center of Oncology, Chief Oncologist 



References

1. Бесова Н.С., Бяхов М.Ю., Горбунова В.А. и др. Клинические рекомендации по диагностике и лечению больных раком желудка. Москва, 2014. 22 с. [Besova N.S., Byakhov M.Yu., Gorbunova V.A. et al. Klinicheskie rekomendatsii po diagnostike i lecheniyu bol’nykh rakom zheludka. Moscow, 2014. 22 p. (In Russ.)].

2. Barber M., Fitzgerald R.C., Caldas C. Familial gastric cancer aetiology and pathogenesis. Best Pract. Res. Clin. Gastroen. terol. 2006. P. 721734.

3. Bernstein C., Bernstein H., Payne C.M., Dvorak K., Garewal H. Field defects in progression to gastrointestinal tract cancers. Cancer Lett. 2008. Vol. 260. P. 110.

4. Состояние онкологической помощи населению России в 2015 году / под редакцией А.Д. Карпина, В.В. Старинского, Г.В. Петровой. М.: МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИРЦ» Минздрава России, 2016. 236 с. [Sostoyanie onkologicheskoy pomoshchi naseleniyu Rossii v 2015 godu. Eds.A. D. Karpin, V.V. Starinskiy, G.V. Petrova. Moscow: P.A. Hertsen Moscow Oncology Research Center, 2016. 236 p. (In Rus.)].

5. Parkin D.M. International variation. Oncogene. 2004. Vol. 23. P. 63296340.

6. Parkin D.M., Bray F., Ferlay J., Pisani P. Global cancer statistics, 2002. CA Cancer J. Clin. 2005. Vol. 55 (2). P. 74–108.

7. Имянитов Е.И. Эпидемиология и биология рака желудка. Практическая онкология. 2009. Т. 10. №1. С. 1–7. [Imyanitov E. I. Epidemiologiya i biologiya raka zheludka. Prakticheskaya onkologiya. 2009. Vol. 10. No. 1. P. 1–7. (In Russ.)].

8. Злокачественные новообразования в России в 2015 году (заболеваемость и смертность) / под ред. А.Д. Карпина, В.В. Старинского, Г.В. Петровой. М.: МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИРЦ» Минздрава России, 2016. 250 с. [Zlokachestvennye novoobrazovaniya v Rossii v 2015 godu (zabolevaemost’ i smertnost’) Eds.A. D. Karpin, V.V. Starinskiy, G.V. Petrova. Moscow: P.A. Hertsen Moscow Oncology Research Center, 2016. 250 p. (In Rus.)] .

9. Park D. I., Yun J.W., Park J.H., Oh S. J., Kim H. J., Cho Y.K., Sohn C. I., Jeon W.K., Kim B. I., Yoo C.H., Son B.H., Cho E.Y., Chae S.W., Kim E. J., Sohn J.H., Ryu S.H., Sepulveda A.R. HER2 / neu amplification is an independent prognostic factor in gastric cance. Dig.Dis. Sci. 2006. Vol. 51. P. 1371–1379.

10. Smyth E.C., Verheij M., Allum W., Cunningham D., Cervantes A., Arnold D. Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology. 2016. Vol. 27. Suppl. 5. P. v38 – v49. doi:10.1093 / annonc / mdw350.

11. Практические рекомендации по лекарственному лечению злокачественных опухолей (RUSSCO) / под ред. В.М. Моисеенко. М.: Общероссийская общественная организация «Российское общество клинической онкологии», 2015. 456 с. [Prakticheskie rekomendatsii po lekarstvennomu lecheniyu zlokachestvennykh opukholey (RUSSCO). Ed.V. M. Moiseenko. Moscow: Obshcherossiyskaya obshchestvennaya organizatsiya “Rossiyskoe obshchestvo klinicheskoy onkologii”, 2015. 456 p. (In Russ.)].

12. He X. K., Sun L. M. The increasing trend in the incidence of gastric cancer in the young population, not only in young Hispanic men. Gastric Cancer. 2017. Vol. 20. P. 1010.

13. Cavallo J. Classifying Gastric Cancers by Subtype May Provide Tailored Treatment Options. ASCO-POST. Last updated 27.07.2017.

14. Huang Q., Shi J., Feng A. et al. Gastric cardiac carcinomas involving the esophagus are more adequately staged as gastric cancers by the 7th edition of the American Joint Commission on Cancer Staging System. Mod Patho. 2011. Vol. 24. P. 138–146.

15. Sano T., Coit D.G., Kim H.H. et al. Gastric Cancer. 2017. Vol. 20. P. 217. https://doi.org / 10.1007 / s10120 016 0601 9.


Review

For citations:


Protasova A.E., Semenova I.V., Raskin G.A., Mukhina M.S., Kuzmina N.S., Orlova R.V. Metastasis of gastric adenocarcinoma in the endometrium and the cervix. Сlinical case. Malignant tumours. 2018;8(1):66-70. (In Russ.) https://doi.org/10.18027/2224-5057-2018-8-1-66-70

Views: 1458


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2224-5057 (Print)
ISSN 2587-6813 (Online)