Sentinel lymph nodes biopsy in early breast cancer and melanoma patients using “Tehnefit 99mTc” radioactive colloid technetium 99mTc
https://doi.org/10.18027/2224-5057-2016-3-67-79
Abstract
The possibilities and technique of using the radioactive colloid technetium99mTc “Tehnefit 99mTc” to identify and 35 biopsy of sentinel lymph nodes with their morphological examination during operations in patients with early breast cancer and melanoma were studied. The optimal dosage of the active volume and the features the injection of the radioactive colloid for sentinel lymph nodes biopsy using “Technetium99mTc” in patients with breast cancer and melanoma with the best results in the Trial № 1 was determined. The most reliable results of histological and cytological intraoperative examination of sentinel lymph nodes in the diagnosis of metastases was the best in using a combination of both methods. The results of Trials in using radioactive colloid technetium99mTc “Tehnefit 99mTc” to identify and biopsy with morphological examination of sentinel lymph nodes in patients with early breast cancer and melanoma did not display the same results that been compared to the special characteristics of their foreign counterparts, reflecting the impossibility of its use in the diagnosis of metastases in the lymph nodes.
About the Authors
A. V. ERMAKOVRussian Federation
MD, PhD, researcher
A. D. ZIKIRYAHODZHAEV
Russian Federation
MD, PhD, DSc, head of dept.
T. N. LAZUTINA
Russian Federation
MD, PhD, researcher
A. V. LEONTYEV
Russian Federation
MD, PhD, head of dept.
N. N. VOLCHENKO
Russian Federation
MD, PhD, DSc, professor, head of dept.
M. M. BELYAKOV
Russian Federation
MD, PhD, researcher
A. D. KAPRIN
Russian Federation
MD, PhD, professor, corresponding member of. Russian Academy of Sciences, director
A. A. KOSTIN
Russian Federation
MD, PhD, professor, deputy director
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Review
For citations:
ERMAKOV A.V., ZIKIRYAHODZHAEV A.D., LAZUTINA T.N., LEONTYEV A.V., VOLCHENKO N.N., BELYAKOV M.M., KAPRIN A.D., KOSTIN A.A. Sentinel lymph nodes biopsy in early breast cancer and melanoma patients using “Tehnefit 99mTc” radioactive colloid technetium 99mTc. Malignant tumours. 2016;(3):67-79. (In Russ.) https://doi.org/10.18027/2224-5057-2016-3-67-79