Новые возможности в коррекции микронутриентной недостаточности у больных со злокачественными новообразованиями


https://doi.org/10.18027/2224-5057-2016-2-55-65

Полный текст:


Аннотация

Метаболизм опухолевых клеток при онкологических заболеваниях является причиной дефицита микронутриентов, особенно при распространенном опухолевом процессе. На сегодняшний день доказано, что у пациентов со злокачественными новообразованиями имеется дефицит отдельных аминокислот (глицин, аргинин, цистеин, аспарагин, лизин, метионин), витаминов (С, Е, D, группы B) и ряда микроэлементов (цинк, марганец, селен). К сожалению, проблеме микронутриентного дефицита и необходимости ее коррекции при онкологических заболеваниях не уделяется должного внимания. В современных исследованиях, в частности, проведенных у больных гепатоцеллюлярной карциномой в терминальной стадии, показано, что использование препаратов, влияющих на микронутриентный метаболизм (например, Онкоксин), позволяет увеличить аппетит, улучшить качество жизни, общее самочувствие и 2-месячную выживаемость. Таким образом, рациональная коррекция определенных микронутриентов может положительно влиять на общее состояние больных, результаты лечения и открывает новые перспективы в коррекции нарушений метаболизма у онкологических больных.

Об авторах

Майя Джугашвили
Мадридский институт онкологии (GrupoImo), Мурсия, Испания
Испания
к. м.н., радиационный онколог


Вадим Сергеевич Покровский
Научно-исследовательский институт экспериментальной диагностики и терапии опухолей, Федеральное государственное бюджетное учреждение «Российский онкологический научный центр имени Н. Н. Блохина» Минздрава России
Россия
д. м.н., старший научный сотрудник лаборатории комбинированной терапии опухолей


Антон Владимирович Снеговой
Федеральное государственное бюджетное учреждение «Российский онкологический научный центр имени Н. Н. Блохина» Минздрава России
Россия
к. м.н., старший научный сотрудник отделения амбулаторной химиотерапии (дневной стационар)


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Дополнительные файлы

Для цитирования: Джугашвили М., Покровский В.С., Снеговой А.В. Новые возможности в коррекции микронутриентной недостаточности у больных со злокачественными новообразованиями. Злокачественные опухоли. 2016;(2):55-65. https://doi.org/10.18027/2224-5057-2016-2-55-65

For citation: Dzhugashvili M., Pokrovsky V.S., Snegovoy A.V. Novel approaches for the correction of micronutrient deficiency in patients with malignant tumors. Malignant tumours. 2016;(2):55-65. (In Russ.) https://doi.org/10.18027/2224-5057-2016-2-55-65

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