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Lymphadenectomy in breast cancer: pros and cons

https://doi.org/10.18027/2224-5057-2016-2-37-42

Abstract

Today one of the discussed issues of surgical treatment of primary operable breast cancer is the appropriateness of performing lymphadenectomy in different volumes. Conducting mammographic screening increases the proportion of patients with minimal breast cancer in which a standard lymphadenectomy in the majority of cases is excessive and crippling procedure. We have analyzed the results of several multicenter studies, which in our opinion have changed the attitude of clinicians to the advisability and scope of lymphadenectomy.

About the Authors

Igor Konstantinovich Vorotnikov
Federal state institution Russian oncological scientific center named. N. N. Blokhin
Russian Federation

MD, PhD, DSc, Professor, head.surgical Department No. 5



Nino Valerianovna Chkhikvadze
Federal state institution Russian oncological scientific center named. N. N. Blokhin
Russian Federation

MD, PhD, doctor of the surgical Department № 5



Denis Anatolevich Ryabchikov
Federal state institution Russian oncological scientific center named. N. N. Blokhin
Russian Federation

MD, PhD, senior researcher of the surgical Department № 5



References

1. Аксель Е. М. Злокачественные образования молочной железы: Состояние онкологической помощи, заболеваемость и смертность. Маммология. 2006; (1): 9–15. Axel E. M. Malignant tumors of the breast: State of cancer care, morbidity and mortality. Mammalogy. 2006; (1): 9–15.

2. Давыдов М. И., Аксель Е. М. Статистика злокачественных новообразований в России и странах СНГ. Вестник РОНЦ им. Н. Н. Блохина РАМН. 2010: 21(2): (прил. 1). Davydov M. I., Aksel E. M. Statistics of malignant neoplasms in Russia and CIS countries. Bulletin of ronts. N. N. Blokhin of the RAMS. 2010: 21(2): (ADJ. 1).

3. Кулигина Е. Ш. Эпидемиологические и молекулярные аспекты рака молочной железы. Практическая онкология. 2010; 11(4):203–216.

4. Kuligina, E. S. Epidemiological and molecular aspects of breast cancer. Practical Oncology. 2010; 11(4):203–216.

5. Семиглазов В. Ф. и др., Проблемы хирургического лечения рака молочной железы. Практическая онкология. 2010; 11(4):217–220. Semiglazov V. F. and others, Problems of surgical treatment of breast cancer. Practical Oncology. 2010; 11(4):217–220.

6. Peitzsch C, Kurth I, Kunz-Schughart L, Baumann M, Dubrovska A. Discovery of the cancer stem cell related determinants of radioresistance. Radiother Oncol 2013;10(8):378–387.

7. Пролиферативные и иммунологические характеристики молекулярно-биологических подтипов рака молочной железы. Новикова И. А., Шатова Ю. С., Златник Е. Ю., Пржедецкий Ю. В., Ульянова Е. П., Черникова Е. Н. Международный журнал прикладных и фундаментальных. 2014; 11:116–119. Novikova I. A., Shatov S., E. J. Zlatnik, Przelecki Y. V., ul’yanova, E. P., Chernikova E. N. Proliferative and immunological characteristics of molecular-biological subtypes of breast cancer international journal of applied and fundamental. 2014; 11:116–119.

8. Halsted W. S. The results of radical operations for the cure of cancer of the breast. Ann.Surg 1907; 46:1–5.

9. B. Fisher, et al. Twenty-Five-Year Follow-up of a Randomized Trial Comparing Radical Mastectomy, Total Mastectomy, and Total Mastectomy Followed by Irradiation. N. Engl. Med., 2002; 347(8): 567–575.

10. Orr RK. The impact of prophylactic axillary node dissection on breast cancer survival: a Bayesian meta-analysis. Ann Surg Oncol. 1999; 6109: 116–27.

11. Rag et al. Ann of Surg Oncol. 2003; 10 (10): 1–8.

12. A.E. Giuliano et al., Axillary Dissection vs No Axillary Dissection in Women With Invasive Breast Cancer and Sentinel Node Metastasis. JAMA. 2011;305(6): 569–575.

13. Семиглазов В. Ф. и др. Общие рекомендации по лечению раннего рака молочной железы St. Gallen‑2015, адаптированные экспертами Российского общества онкомаммологов. Oпухоли женской репродуктивной системы. 2015; 3: 43–60. Semiglazov V. F., et al. General recommendations for treatment of early breast cancer St. Gallen‑2015 adapted by experts of Russian society of oncomammology. Tumors of the female reproductive system. 2015; 3: 43–60.

14. Иванов В. М., Летягин В. П., Высоцкая И. В., Погодина Е. М., Абашин С. Ю., Перадзе Н. А. Лечение рака молочной железы у больных пожилого и старческого возраста. Монография. Москва 2001; 9–45. Ivanov V. M, Letyagin V. P., Vysotskaya I. V., Pogodin, E. M., Abashin S. Yu., Peradze N.. The treatment of breast cancer patients of elderly and senile age. Monograph. Moscow 2001; 9–45.

15. C una G., Treatment of breast cancer in in elderly patients. J. Surg.Oncol. 1993; 103(4):379–85.

16. Martelli G. et al. Axillary Dissection Versus No Axillary Dissection in Elderly Patients with Breast Cancer and No Palpable Axillary Nodes: Results After 15 Years of Follow-Up. Ann Surg Oncol. 2011; 18(1): 125–133.


Review

For citations:


Vorotnikov I.K., Chkhikvadze N.V., Ryabchikov D.A. Lymphadenectomy in breast cancer: pros and cons. Malignant tumours. 2016;(2):37-42. (In Russ.) https://doi.org/10.18027/2224-5057-2016-2-37-42

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ISSN 2224-5057 (Print)
ISSN 2587-6813 (Online)