The impact of time of performance of delayed orchiectomy on survival of patients with advanced germ cell tumors of testicles
https://doi.org/10.18027/2224-5057-2014-2-3-10
Abstract
Aim: To investigate the impact of time of performance of delayed orchiectomy on overall survival of patients with advanced germ cell tumors of testicle who didn’t undergo surgery before starting of treatment.
Materials and methods: From 1986 to 2010 in the department of clinical pharmacology and chemotherapy 71 (4,8%) of 1486 patients underwent delayed orchiectomy. During the first course of chemotherapy (1st group) 39 (55%) patients underwent surgery, 21 (29,6%) patients - during 2nd -4th courses (2nd group), after the ending of chemotherapy – 11 (15,5%) patients (3rd group).
Results: Final histological investigation of the specimens revealed viable germ cell tumor in 25 (64,1%) patients in the 1st group, in 10 (47,7%) patients in the 2nd group and no viable tumor in the 3rd group.
Conclusion: Performance of orchiectomy simultaneously with the removal of the other sites of the tumor after chemotherapy doesn’t impair survival.
About the Authors
M. Yu. Fedyanin
Российский онкологический научный центр им. Н. Н. Блохина
Russian Federation
Russian Federation
A. A. Tryakin
Российский онкологический научный центр им. Н. Н. Блохина
Russian Federation
Russian Federation
A. A. Bulanov
Российский онкологический научный центр им. Н. Н. Блохина
Russian Federation
Russian Federation
I. A. Fainshtein
Российский онкологический научный центр им. Н. Н. Блохина
Russian Federation
Russian Federation
Yu. S. Sergeev
Российский онкологический научный центр им. Н. Н. Блохина
Russian Federation
Russian Federation
V. B. Matveev
Российский онкологический научный центр им. Н. Н. Блохина
Russian Federation
Russian Federation
A. M. Garin
Российский онкологический научный центр им. Н. Н. Блохина
Russian Federation
Russian Federation
S. A. Tyulyandin
Российский онкологический научный центр им. Н. Н. Блохина
Russian Federation
Russian Federation
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Review
For citations:
Fedyanin M.Yu., Tryakin A.A., Bulanov A.A., Fainshtein I.A., Sergeev Yu.S., Matveev V.B., Garin A.M., Tyulyandin S.A. The impact of time of performance of delayed orchiectomy on survival of patients with advanced germ cell tumors of testicles. Malignant tumours. 2014;(2):3-10. (In Russ.) https://doi.org/10.18027/2224-5057-2014-2-3-10
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