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RADIOTHERAPY AFTER ORGAN-SPARING SURGERY FOR I-IIA STAGES OF LEFT-SIDED BREAST CANCER

https://doi.org/10.18027/2224-5057-2017-7-4-05-12

Abstract

Breast preserving surgery became a preferable method of treatment for breast cancer now. Adjuvant radiotherapy in breast cancer patients is a standard component of breast-preserving treatment that reduces the recurrence rate and mortality. The risk of cardiotoxicity after radiation therapy for left-sided breast cancer is high. The deep inspiration breath hold technique is used to reduce radiation dose to the heart. The Real-time Position Management, Respiratory Gating (RPM; Varian) system is used to monitor respiratory motion. Audio supporting system as a part of RPM has some technical lacks. The purpose of our research consists in developing video engineering system to control respiratory movements. Use of this system allowed patients to  observe graphical sinusoid of amplitudes inspiration image in time interval. Also such system allowed to achieve shortening of treatment time and decrease psychological and emotional stress of the patients.

About the Authors

I. A. Gladilina
N. N. Blokhin Russian Cancer Research Center
Russian Federation

Irina A. Gladilina - MD, DSc Med, Leading Researcher of the Department of Radiosurgery.

Moscow



D. I. Fedoseenko
N. N. Blokhin Russian Cancer Research Center
Russian Federation

Dmitriy I. Fedoseenko - MD, Department of Radiosurgery.

Moscow



E. S. Makarov
N. N. Blokhin Russian Cancer Research Center
Russian Federation

Mikhail A. Shabanov - Leading Researcher of Human Pathological Anatomy Department.

Moscow



M. A. Shabanov
N. N. Blokhin Russian Cancer Research Center
Russian Federation

Evgeniy S. Makarov - MD, PhD Med, Senior Researcher of the Department of Radiosurgery.

Moscow



R. K. Valiev
N. N. Blokhin Russian Cancer Research Center
Russian Federation

Ramiz K. Valiev - MD, PhD Med, Head of the Department of Radiosurgery.

Moscow



G. A. Tkachenko
N. N. Blokhin Russian Cancer Research Center
Russian Federation

Galina A. Tkachenko - MD, PhD, Medical Psychologist of the Rehabilitation Department of the Division of Functional Diagnostics, Intensive Сare and Rehabilitation.

Moscow



M. I. Nechushkin
N. N. Blokhin Russian Cancer Research Center
Russian Federation

Mikhail I. Nechushkin - MD, DSc Med, Leading Researcher of the Department of Radiosurgery.

Moscow



References

1. Liljegren G., Holmberg L., Bergh J., Lindgren A. et al. 10-Year Results After Sector Resection With or Without Postoperative Radiotherapy for Stage I Breast Cancer: A Randomized Trial, Journal of Clinical Oncology, 1999, Vol. 17, No. 8, pp. 2326–2329.

2. Darby S., McGale P., Correa C., Collaborative Group (EBCTCG). Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials, Early Breast Cancer Trialists, Lancet, 2011, No. 378 (9804), pp. 1707–1716.

3. Taylor C., Correa C., Duane F.K., Aznar M.C., Anderson S.G., Bergh J. Estimating the Risks of Breast Cancer Radiotherapy: Evidence From Modern Radiation Doses to the Lungs and Heart and From Previous Randomized Trials, Journal of Clinical Oncology, 2017, Vol. 35, No. 15, pp. 1641–1649.

4. van den Bogaard V.A. B., Bastiaan D.P., van der Schaaf T., Bouma A.A. B., Middag A.M. H., Bantema-Joppe E. J. Validation and Modification of a Prediction Model for Acute Cardiac Events in Patients With Breast Cancer Treated With Radiotherapy Based on Three-Dimensional Dose Distributions to Cardiac Substructures, Journal of Clinical Oncology, 2017, Vol. 35, No. 11, pp. 1171–1178.

5. Recht А. Radiation-Induced Heart Disease After Breast Cancer Treatment: How Big a Problem, and How Much Can and Should We Try to Reduce It? Journal of clinical oncology, 2017, Vol. 35, No. 11, pp. 1146–1148.

6. Henson K. E., McGale P., Taylor C., Darby S.C. Radiation-related mortality from heart disease and lung cancer more than 20 years after radiotherapy for breast cancer, Br. J. Cancer, 2013, Vol. 108, pp. 179–182.

7. Wright P.G., Drinane J. J., Sobel H. L., Chung M.H. Left-sided breast irradiation does not result in increased long-term cardiac-related mortality among women treated with breast-conserving surgery, Ann. Surg. Oncol., 2016, Vol. 23, pp. 1117–1122.

8. Boero I. J., Paravati A. J., Triplett D.P., Hwang L., Matsuno R.K., Gillespie E. F. et al. Modern radiation therapy and cardiac outcomes in breast cancer, Int. J. Radiat. Oncol. Biol. Phys., 2016, Vol. 94, pp. 700–708.

9. Boekel N.B., Schaapveld M., Gietema J.A., Russell N.S., Poortmans P., Theuws J.C. et al. Cardiovascular disease risk in a large, population-based cohort of breast cancer survivors, Int. J. Radiat. Oncol. Biol. Phys., 2016, Vol. 94, pp. 1061–1072.

10. Handbook of Evidence-Based Stereotactic Radiosurgery and Stereotactic Body Radiotherapy. Eds. Sethi R.A., Barani I. J., Larson D.A., Roach M., Springer International Publishing Switzerland, 2016, pp. 11–19.

11. Latty D., Stuart K. E., Wang W., Ahern V. Review of deep inspiration breath-hold techniques for the treatment of breast cancer, Journal of Medical Radiation Sciences, 2015, Vol. 62 (1), pp. 74–81.

12. Principles and Practice of Radiation Oncology. Eds. Halperin E.C., Wazer D. E., Perez C.A., Brady L.W., Wolters Kluwer/Lippincott Williams & Wilkins, 2013, pp. 7.

13. Rusthoven K. E., Kavanagh B.D., Cardenes H., Stieber V.W., Burri S.H., Feigenberg S. J. et al. Multi-institutional Phase I/II trial of stereotactic body radiation therapy for liver metastases, J. Clin. Oncol., 2009, Vol. 27, pp. 1572–1578.

14. Батаршев А.В. Базовые психологические свойства и самоопределение личности: Практическое руководство по психологической диагностике // СПб.: Речь, 2005, С. 44–49. [Batarshev A.V. Bazovye psikhologicheskie svoystva i samoopredelenie lichnosti: Prakticheskoe rukovodstvo po psikhologicheskoy diagnostike, Saint Petersburg: Rech’, 2005, pp. 44–49 (In Russ.)].

15. Huskisson E.C. Measurement of pain, Lancet, 1974, Nov 9, Vol. 2 (7889), pp. 1127–1131.


Review

For citations:


Gladilina I.A., Fedoseenko D.I., Makarov E.S., Shabanov M.A., Valiev R.K., Tkachenko G.A., Nechushkin M.I. RADIOTHERAPY AFTER ORGAN-SPARING SURGERY FOR I-IIA STAGES OF LEFT-SIDED BREAST CANCER. Malignant tumours. 2017;7(4):5-12. (In Russ.) https://doi.org/10.18027/2224-5057-2017-7-4-05-12

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ISSN 2224-5057 (Print)
ISSN 2587-6813 (Online)