Preview

Malignant tumours

Advanced search

Complex surgical treatment of giant retroperitoneal liposarcoma: a clinical case

https://doi.org/10.18027/2224-5057-2025-059

Abstract

Retroperitoneal liposarcoma is a rare malignancy with a high recurrence rate. Giant retroperitoneal liposarcoma presents significant challenges for oncologists due to its invasive nature and compression of vital organs. Early diagnosis and complete surgical removal of the tumor are key factors in the successful treatment of this disease. This case demonstrates the complexity of treating a 65‑year‑old woman with a tumor measuring 31 × 26 × 17 cm, weighing 5.9 kg. It highlights the importance of precision and complexity of surgical intervention, as well as the potential of using 3D tumor modeling to calculate tumor volume, intraoperative blood loss, surgical planning, and predict complications.

About the Authors

A.  N. Zhigulev
Perm State Medical University named after Academician E. A. Wagner; Perm Regional Oncological Dispensary
Russian Federation

Zhigulev Anton Nikolaevich

26 Petropalovskaya St., Perm 614990, Russia; 
15 Baumana St., Perm 614066, Russia


Competing Interests:

The authors declare that there are no possible conflicts of interest.



I.  A. Balandina
Perm State Medical University named after Academician E. A. Wagner
Russian Federation

Balandina Irina Anatolyevna

26 Petropalovskaya St., Perm 614990, Russia


Competing Interests:

The authors declare that there are no possible conflicts of interest.



D.  D. Shlyakov
Perm State Medical University named after Academician E. A. Wagner; Perm Regional Oncological Dispensary
Russian Federation

26 Petropalovskaya St., Perm 614990, Russia; 
15 Baumana St., Perm 614066, Russia


Competing Interests:

The authors declare that there are no possible conflicts of interest.



A.  A. Dovbysh
Perm Regional Oncological Dispensary
Russian Federation

Dovbysh Anastasia Alexandrovna

15 Baumana St., Perm 614066, Russia


Competing Interests:

The authors declare that there are no possible conflicts of interest.



References

1. Benberin V.V., Baizakov B.T., Shanazarov N.A., Zinchenko S.V. Soft tissue sarcoma: a modern view to the problem. Avicenna Bulletin 2019;21(2):291–1 (In Russ). http://dx.doi.org/10.25005/2074-0581-2019-21-2-291-297

2. Blay J.Y., Honore C., Stoeckle E., et al. Surgery in reference centers improves survival of sarcoma patients: a nationwide study. Ann Oncol 2019;30(7):1143–1153. https://doi.org/10.1093/annonc/mdz124

3. Clinical Guidelines. Retroperitoneal non-organ sarcomas, 2024. Available at: https://cr.minzdrav.gov.ru/preview-cr/618_3(In Russ.)

4. Francis I.R., Cohan R.H., Varma D.G., Sondak V.K. Retroperitoneal sarcomas. Cancer Imaging 2005;5(1):89–94. https://doi.org/10.1102/1470-7330.2005.0019

5. Oh S.D., Oh S.J., Suh B.J., et al. A giant retroperitoneal liposarcoma encasing the entire left kidney and adherent to adjacent structures: a case report. Case Rep Oncol 2016;9(2):368–372. https://doi.org/10.1159/000447488

6. Volkov A.Yu., Nered S.N., Kozlov N.A., et al. Active surgical approach for retroperitoneal liposarcoma. Pirogov Russian Journal of Surgery 2021;11(5):5–11 (In Russ.). https://doi.org/10.17116/hirurgia20211115

7. Yokoyama Y., Nishida Y., Ikuta K., et al. A case of retroperitoneal dedifferentiated liposarcoma successfully treated by neoadjuvant chemotherapy and subsequent surgery. Surg Case Rep 2020;6(1):105. https://doi.org/10.1186/s40792-020-00865-2

8. Gronchi A., Miceli R., Allard M.A., et al. Personalizing the approach to retroperitoneal soft tissue sarcoma: histology-specific patterns of failure and postrelapse outcome after primary extended resection. Ann Surg Oncol 2015;22(5):1447–54. https://doi.org/10.1245/s10434-014-4130-7

9. Echenique-Elizondo M., Amondarain-Arratibel J.A. Giant retroperitoneal liposarcoma. Cir Esp 2005;77(5):293–295. https://doi.org/10.1016/s0009-739x(05)70857-5

10. Интерактивный графический универсальный программный комплекс измерения анатомический структур. Жигулев А.Н., Баландин А.А., Баландина И.А., Селина А.Д., Свидетельство о регистрации программы для ЭВМ RU 2025619366, 16.04.2025.

11. Zhang W.D., Liu D.R., Que R.S., et al. Management of retroperitoneal liposarcoma: a case report and review of the literature. Oncol Lett 2015;10(1):405–409. https://doi.org/10.3892/ol.2015.3193


Review

For citations:


Zhigulev A.N., Balandina I.A., Shlyakov D.D., Dovbysh A.A. Complex surgical treatment of giant retroperitoneal liposarcoma: a clinical case. Malignant tumours. (In Russ.) https://doi.org/10.18027/2224-5057-2025-059

Views: 10


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2224-5057 (Print)
ISSN 2587-6813 (Online)