Новые возможности органосохраняющего лечения локализованного почечно-клеточного рака и его рецидива


https://doi.org/10.18027/2224-5057-2011-1-11-20

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Аннотация

Последнее десятилетие было ознаменовано более глубоким пониманием молекулярных путей, ответственных за развитие почечно-клеточного рака (ПКР), достижениями в системном лечении диссеминированного ПКР, а также многочисленными дискуссиями по поводу выбора наиболее оптимального варианта лечения локализованных форм опухоли. Учитывая многочисленные данные о развитии почечной недостаточности после хирургического лечения, а также возрастающее количество пациентов с ранними стадиями ПКР, важность органосохраняющего лечения нельзя недооценивать. Несмотря на отсутствие рандомизированных исследований, сравнивающих эффективность органосохраняющего лечения и радикальной нефрэктомии при ПКР, многочисленные ретроспективные данные указывают на сопоставимую эффективность обоих лечебных подходов при лучших показателях функции почек в случае органосохраняющего лечения. Поэтому органосохраняющее лечение все чаще используется как для открытых, так и для малоинвазивных хирургических вмешательств. В данном обзоре будут представлены данные, подтверждающие необходимость органосохраняющего лечения при ПКР, и описаны новые возможности метода, включая лапароскопические методики с участием роботизированной техники, аблацию и повторные хирургические вмешательства на почке. 


Об авторах

GENNADY BRATSLAVSKY
Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, 10 Center Drive MSC 1107, Building 10, CRC, Room 2W- 5942, Bethesda, Maryland 20892-1107.
Соединённые Штаты Америки


RONALD BORIS
National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Соединённые Штаты Америки


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Для цитирования: BRATSLAVSKY G., BORIS R. Новые возможности органосохраняющего лечения локализованного почечно-клеточного рака и его рецидива. Злокачественные опухоли. 2011;1(1):11-20. https://doi.org/10.18027/2224-5057-2011-1-11-20

For citation: ., . . Malignant tumours. 2011;1(1):11-20. (In Russ.) https://doi.org/10.18027/2224-5057-2011-1-11-20

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