tumorsMalignant tumoursMalignant tumours2224-50572587-6813Rosoncoweb10.18027/2224-5057-2021-11-4-14-22tumors-926Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL REPORTSМЕТОДОЛОГИЯ РАСЧЕТА ПЛОЩАДИ ЛОКАЛЬНОГО ОТЕКА КОЖИ ПРИ РАКЕ МОЛОЧНОЙ ЖЕЛЕЗЫMETHODOLOGY FOR LOCAL SKIN EDEMA CALCULATING IN BREAST CANCERАмосоваВ. А.AmosovaV. A.

Виктория А. Амосова, аспирант, врач-онколог, отдел телемедицины

Москва

Viktoriya A. Amosova, Postgraduate Student, Oncologist, Telemedicine Department

Moscow

amosova_va@mail.ruЗагаштоковаА. К.ZagashtokovaA. K.

Альбина К. Загаштокова, аспирант

Москва

Albina K. Zagashtokova, Postgraduate Student

Moscow

КарповаМ. С.KarpovaM. S.

Марина С. Карпова, к. м. н., врач-рентгенолог, рентгендиагностическое отделение

Москва

Marina S. Karpova, MD, PhD, Radiologist, Radiodiagnosis Department

Moscow

ПонедельниковаН. В.PonedelnikovaN. V.

Наталия В. Понедельникова, к. м. н., врач-рентгенолог, рентгендиагностическое отделение

Москва

Natalia V. Ponedelnikova, MD, PhD, Radiologist, Radiodiagnosis Department

Moscow

КасымоваА. А.KasimovaA. A.

Анастасия А. Касымова, врач-рентгенолог, рентгендиагностическое отделение

Москва

Anastasia A. Kasimova, Radiologist, Radiodiagnosis Department

Moscow

ТрофимоваО. П.TrofimovaO. P.

Оксана П. Трофимова, д. м. н., ведущий научный сотрудник отделения радиотерапии, врач-радиотерапевт, ФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава России; профессор кафедры онкологии и паллиативной медицины им. А. И. Савицкого РМА НПО Минздрава РФ

Москва

Oksana P. Trofimova, MD, PhD, DSc, Leading Researcher of the Department of Radiotherapy, Radiotherapist, N. N. Blokh‑ in National Medical Research Center of Oncology; Professor, Department of Oncology and Palliative Medicine named after A. I. Savitsky, Russian Medical Academy of Continuous Professional Education of the Ministry of Health of Russia

Moscow

ФроловаМ. А.FrolovaM. A.

Мона А. Фролова, д. м. н., ведущий научный сотрудник химиотерапевтического отделения № 1

Москва

Mona A. Frolova, MD, PhD, DSc, Leading Research Associate, Chemotherapy Department No. 1

Moscow

МакаровЕ. С.MakarovE. S.

Евгений С. Макаров, к. м. н., старший научный сотрудник хирургического отделения № 15 (комбинированного лечения опухолей молочной железы)

Москва

Evgeniy S. Makarov, MD, PhD, Senior Researcher, Department of Surgery No. 15 (Combined Treatment of Breast Tumors)

Moscow

ПетровскийА. В.PetrovskyA. V.

Александр В. Петровский, к. м. н., заместитель директора по образовательной деятельности, заведующий отделением комбинированного лечения опухолей молочной железы, ФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава России; доцент кафедры онкологии Института Клинической Медицины, ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава России (Сеченовский Университет)

Москва

Alexander V. Petrovsky, MD, PhD, Deputy Director for Education, Head of the Department of Combined Treatment of Breast Tumors, N. N. Blokhin National Medical Research Center of Oncology, Associate Professor, Department of Oncology, Institute of Clinical Medicine, I. M. Sechenov First Moscow State Medical University

Moscow

ФГБУ «НМИЦ онкологии им. Н. Н. Блохина» Минздрава РоссииРоссияN. N. Blokhin National Medical Research Center of OncologyRussian FederationФГБУ «НМИЦ онкологии им. Н. Н. Блохина» Минздрава России; ФГАОУ ВО «Первый МГМУ им. И. М. Сеченова» Минздрава России (Сеченовский Университет)РоссияN. N. Blokhin National Medical Research Center of Oncology; I. M. Sechenov First Moscow State Medical UniversityRussian Federation2021030220221141422Copyright © Амосова В.А., Загаштокова А.К., Карпова М.С., Понедельникова Н.В., Касымова А.А., Трофимова О.П., Фролова М.А., Макаров Е.С., Петровский А.В., 20222022Амосова В.А., Загаштокова А.К., Карпова М.С., Понедельникова Н.В., Касымова А.А., Трофимова О.П., Фролова М.А., Макаров Е.С., Петровский А.В.Amosova V.A., Zagashtokova A.K., Karpova M.S., Ponedelnikova N.V., Kasimova A.A., Trofimova O.P., Frolova M.A., Makarov E.S., Petrovsky A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.malignanttumors.org/jour/article/view/926

Рак молочной железы с вовлечением кожи — одна из наименее изученных и, в то же время, сложно поддающихся лечению форм. Несмотря на достижения современной диагностики, многие вопросы, касающиеся определения степени выраженности отека кожи и количественной оценки динамики на фоне неоадъювантной лекарственной терапии, зачастую вызывают ряд сложностей. В свою очередь, это может привести как к неправильному стадированию и «перелечиванию» пациентов, так и к субъективности в оценке ответа на проводимое лечение. Ранее были предложены различные подходы для расчета степени выраженности отека, однако широкого распространения они не получили. В данной статье представлен разработанный нами метод, позволяющий определить площадь отека кожи, который в дальнейшем позволит индивидуализировать подходы к лечению.

Breast cancer with skin involvement is one of the least studied and at the same time difficult to treat forms of cancer. Despite the achievements of modern diagnostics, many issues related to skin edema severity evaluation and quantitative assessment of changes associated with neoadjuvant drug therapy often cause a number of difficulties. In turn, this can lead to both incorrect staging and «overtreatment» of patients, as well as subjectivity in assessing the response to the treatment. Various approaches have been proposed to calculate the severity of edema, but they have not been widely accepted. This article presents our method developed for determining the area of skin edema, which in the future will allow individualizing approaches to treatment.

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The authors declare that there are no conflicts of interest present.