tumorsMalignant tumoursMalignant tumours2224-50572587-6813Rosoncoweb10.18027/2224-5057-2019-9-3s1-15-22tumors-659Research ArticleОБЗОРЫ И АНАЛИТИКАREVIEWS AND ANALYSISАДЪЮВАНТНАЯ ТЕРАПИЯ БОЛЬНЫХ РАКОМ ТОЛСТОЙ КИШКИ II СТАДИИ — ТРУДНОЕ РЕШЕНИЕ ДЛЯ ХИМИОТЕРАПЕВТАФедянинМ. Ю.

Москва

fedianinmu@mail.ruФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава РоссииRussian Federation20192611201993s11522Copyright © Федянин М.Ю., 20192019Федянин М.Ю.Федянин М.Ю.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.malignanttumors.org/jour/article/view/659

Несмотря на достижения хирургии и адъювантной химиотерапии показатели 5‑летней общей выживаемости пациентов с резектабельными стадиями рака толстой кишки остаются на уровне 60 %. И наиболее сложная в плане необходимости выбора адъювантной химиотерапии является II стадия заболевания. Поэтому изучение факторов, ассоциированных с прогнозом болезни, именно при II стадии рака толстой кишки, является актуальной задачей. За последние несколько лет выявлены новые прогностические факторы, получены данные о роли циркулирующей опухолевой ДНК в плазме крови при II стадии колоректального рака, представлены новые данные о возможности сокращения длительности адъювантной химиотерапии. Все это определило необходимость пересмотреть алгоритм выбора послеоперационного лечения при II стадии заболевания. Именно этому вопросу и посвящена настоящая статья.

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The authors declare that there are no conflicts of interest present.