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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">tumors</journal-id><journal-title-group><journal-title xml:lang="ru">Malignant tumours</journal-title><trans-title-group xml:lang="en"><trans-title>Malignant tumours</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2224-5057</issn><issn pub-type="epub">2587-6813</issn><publisher><publisher-name>Rosoncoweb</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18027/2224-5057-2019-9-2-35-44</article-id><article-id custom-type="elpub" pub-id-type="custom">tumors-628</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL REPORTS</subject></subj-group></article-categories><title-group><article-title>Реконструкция подбородочного отдела нижней челюсти при опухолях челюстно-лицевой области и слизистой полости рта</article-title><trans-title-group xml:lang="en"><trans-title>Mandibular reconstruction of the chin area in patients with tumors of the maxillofacial region and oral mucosa</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кропотов</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kropotov</surname><given-names>М. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Михаил А. Кропотов - доктор медицинских наук, ведущий научный сотрудник отделения опухолей головы и шеи</p></bio><bio xml:lang="en"><p>Mikhail A. Kropotov - MD, PhD, DSc, Leading research fellow, Head and Neck Cancer Department</p></bio><email xlink:type="simple">drkropotov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соболевский</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sobolevsky</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимир А. Соболевский - доктор медицинских наук, заведующий отделением реконструктивной и пластической хирургии.</p><p>Москва</p></bio><bio xml:lang="en"><p>Vladimir A. Sobolevsky - MD, PhD, DSc, Head of the Reconstructive and Plastic Surgery Department.</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Диков</surname><given-names>Ю. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Dikov</surname><given-names>Yu. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юрий Ю. Диков - кандидат медицинских наук, врач отделения реконструктивной и онкопластической хирургии.</p><p>Москва</p></bio><bio xml:lang="en"><p>Yury Yu. Dikov - MD, PhD, physician, Reconstructive and Plastic Surgery Department.</p></bio><email xlink:type="simple">dikovyura@list.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлева</surname><given-names>Л. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovleva</surname><given-names>L. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лилия П. Яковлева - кандидат медицинских наук, заведующая отделением опухолей головы и шеи</p></bio><bio xml:lang="en"><p>Liliya P. Yakovleva - MD, PhD, Head of the Head and Neck Cancer Department</p></bio><email xlink:type="simple">l.yakovleva@mknc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ходос</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khodos</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Артем В. Ходос - врач отделения опухолей головы и шеи</p></bio><bio xml:lang="en"><p>Artyom V. Khodos - physician, Head and Neck Cancer Department</p></bio><email xlink:type="simple">khodos.av@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаврищук</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gavrishchuk</surname><given-names>P. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петр А. Гаврищук - врач отделения опухолей головы и шеи</p></bio><bio xml:lang="en"><p>Pyotr A. Gavrishchuk - physician, Head and Neck Cancer Department</p></bio><email xlink:type="simple">gavrishchukp@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ «Московский Клинический Научный Центр им. А.С. Логинова» ДЗМ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.S. Loginov Moscow Clinical Scientific Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ онкологии им Н.Н. Блохина» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.N. Blokhin National Medical Research Center of Oncology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>17</day><month>06</month><year>2019</year></pub-date><volume>9</volume><issue>2</issue><fpage>35</fpage><lpage>44</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кропотов М.А., Соболевский В.А., Диков Ю.Ю., Яковлева Л.П., Ходос А.В., Гаврищук П.А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Кропотов М.А., Соболевский В.А., Диков Ю.Ю., Яковлева Л.П., Ходос А.В., Гаврищук П.А.</copyright-holder><copyright-holder xml:lang="en">Kropotov М.А., Sobolevsky V.A., Dikov Y.Y., Yakovleva L.P., Khodos A.V., Gavrishchuk P.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.malignanttumors.org/jour/article/view/628">https://www.malignanttumors.org/jour/article/view/628</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Местнораспространенный плоскоклеточный рак слизистой оболочки полости рта поражает нижнюю челюсть в 13–38% случаев. Выполнение сегментарной резекции нижней челюсти, в частности, в области подбородочного отдела, даже на небольшом протяжении приводит к значительным функциональным и косметическим нарушениям, что требует выполнения одномоментной реконструкции дефекта. Существующие в настоящий момент способы пластического замещения дефектов требуют сравнительной оценки.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Материалом для данной работы послужили результаты лечения больных с опухолями нижней челюсти за период с 1998 по 2018 гг. Выполнено 471 оперативное вмешательство на нижней челюсти, включая краевую резекцию и срединную мандибулотомию; сегментарная резекция выполнялась в 203 случаях (43.1%). Из них мы выделили 99 пациентов, у которых отмечен изолированный дефект подбородочного отдела, либо в комбинации с дефектом тела нижней челюсти, либо субтотальным дефектом.</p></sec><sec><title>Результаты</title><p>Результаты. В своей работе мы провели анализ результатов лечения пациентов с первичными и вторичными опухолями нижней челюсти, при которых поражался подбородочный отдел, как наиболее сложный для реконструкции с точки зрения хирурга и наиболее важный для пациента с функциональной и эстетической точек зрения.</p></sec><sec><title>Выводы</title><p>Выводы. При дефекте подбородочного отдела нижней челюсти необходима одномоментная реконструкция. Методом выбора замещения дефекта является применение реконструктивной пластины с кожно-мышечным лоскутом либо реваскуляризированных костных трансплантатов. При протяженных дефектах нижней челюсти с включением подбородочного отдела предпочтение отдается малоберцовому трансплантату. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Locally advanced squamous cell carcinoma of the oral cavity invades the mandible in 13–38 % of cases. Even a small segmental resection of the mandible, for instance, in the chin area, causes significant functional and cosmetic impairment and requires immediate reconstruction of the bone defect. Currently available methods of defect closure require a comparative assessment.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. This article is based on the outcome data from patients with mandibular tumors treated from 1998 through 2018. We identified 471 cases of mandibular surgery including marginal resection and midline mandibulotomy; 203 (43.1 %) patients underwent segmental resection. Of them, we selected 99 patients with an isolated chin defect combined either with a mandibular body defect or with a subtotal defect in the mandible.</p></sec><sec><title>Results</title><p>Results. In this study, we analyzed the treatment outcomes in patients with primary and secondary mandibular tumors involving the chin as the most difficult for reconstruction from the point of view of the surgeon and the most important for the patient from the functional and aesthetic point of view.</p></sec><sec><title>Conclusions</title><p>Conclusions. A mandibular defect located in the chin area requires immediate reconstruction. The preferable method of defect closure is the application of a reconstruction plate with a musculocutaneous flap or implantation of vascularized bone grafts. Implantation of a fibular free flap is preferable for the closure of extensive mandibular defects involving the chin area. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>опухоли головы и шеи</kwd><kwd>рак полости рта</kwd><kwd>реконструктивная хирургия</kwd><kwd>микрохирургия</kwd><kwd>подбородочный отдел</kwd></kwd-group><kwd-group xml:lang="en"><kwd>head and neck tumors</kwd><kwd>oral carcinoma</kwd><kwd>reconstructive surgery</kwd><kwd>microsurgery</kwd><kwd>the chin</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Brown J.S., Barry C., Ho M. et al. A new classification for mandibular defects after oncological resection. Lancet Oncol. 2016, 17, 23-30.</mixed-citation><mixed-citation xml:lang="en">Brown J.S., Barry C., Ho M. et al. A new classification for mandibular defects after oncological resection. 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