tumorsMalignant tumoursMalignant tumours2224-50572587-6813Rosoncoweb10.18027/2224-5057-2018-8-2-64-75tumors-518Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL REPORTSХИМИОТЕРАПИЯ У ПОЖИЛЫХ ПАЦИЕНТОВ, СТРАДАЮЩИХ РАКОМ ЖЕЛУДКАCHEMOTHERAPY IN ELDERLY PATIENTS WITH STOMACH CANCERКоролеваО. А.KorolevaO. A.

Ольга А. Королева - ординатор кафедры онкологии и торакальной хирургии

Olga A. Koroleva - Resident of the Department of Oncology and Thoracic Surger

olyakoroleva1992@yandex.ruКогонияЛ. М.KogoniyaL. M.

Лали М. Когония - доктор медицинских наук, профессор кафедры онкологии и торакальной хирургии

Lali M. Kogoniya - MD, DSc Med, Professor, Department of Oncology and Thoracic Surgery

lali51@yandex.ruБяховаМ. М.ByakhovaM. M.

Мария М. Бяхова - кандидат медицинских наук, старший научный сотрудник патологоанатомического отделения

Maria M. Byakhova - MD, PhD Med, Senior Researcher, Pathoanatomical Department

biakhovamm@mail.ruТитовА. Г.TitovA. G.

Андрей Г. Титов - кандидат медицинских наук, ассистент кафедры онкологии и торакальной хирургии Московского областного НИКИ им. М. Ф. Владимирского; зав. онкологического отделения ВГБ, филиал ГАУЗ МО КГБ; руководитель филиала кафедры онкологии в ГАУЗ МО КГБ 

Andrey G. Titov - MD, PhD Med, Assistant of the Department of Oncology and Thoracic Surgery, M. F. Vladimirsky MRRCI; Head of the Oncology Department, Vysokovskaya City Hospital, Branch of the lin CH; Head of the Branch of the Oncology Department, Klin CH

agtitov@mail.ruГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского» (МОНИКИ)РоссияM. F. Vladimirsky Moscow Regional Research and Clinical Institute (MONIKI)Russian FederationГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского» (МОНИКИ); Высоковская городская больница, филиал ГАУЗ МО «Клинская городская больница»; ГАУЗ МО Клинская городская больницаРоссияM. F. Vladimirsky Moscow Regional Research and Clinical Institute (MONIKI); Vysokovskaya City Hospital, Branch of the Klin City Hospital; Klin City HospitalRussian Federation201812072018826475Copyright © Королева О.А., Когония Л.М., Бяхова М.М., Титов А.Г., 20182018Королева О.А., Когония Л.М., Бяхова М.М., Титов А.Г.Koroleva O.A., Kogoniya L.M., Byakhova M.M., Titov A.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.malignanttumors.org/jour/article/view/518

Рак желудка (РЖ) является одним из наиболее частых злокачественных заболеваний, возникающих у пожилых людей. Системная химиотерапия показала улучшение качества жизни и выживаемости по сравнению с паллиативной терапией у пациентов с поздними стадиями РЖ. Также было показано, что пожилые пациенты с РЖ способны переносить и получать эффективную системную химиотерапию, как и более молодые пациенты с той же стадией рака. Возрастной ценз не должен быть единственным критерием для исключения эффективной химиотерапии. Тем не менее правильный отбор пациентов чрезвычайно важен для обеспечения эффективного и безопасного лечения. В статье проанализированы оптимальные режимы химиотерапии с учетом показателей общего состояния и гериатрического функционального статуса пациентов пожилого возраста с РЖ.

Stomach cancer (SC) (in the structure of morbidity) is one of the most frequent malignant diseases that occurs in the elderly. Systemic chemotherapy showed improved quality of life and survival rate compared with palliative therapy in patients with advanced SC. It has also been shown that elderly patients with SC are able to tolerate and receive effective systemic chemotherapy, as are the younger patients with the same stage of cancer. The only one age limit should not be the only criterion for excluding effective chemotherapy. However, proper patient selection is extremely important to ensure effective safe treatment. The article analyzes the optimal regimens of chemotherapy, taking into account the general condition and geriatric functional status of elderly patients with SC.

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The authors declare that there are no conflicts of interest present.