tumorsMalignant tumoursMalignant tumours2224-50572587-6813Rosoncoweb10.18027/2224-5057-2017-3-57-61tumors-392Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL REPORTSСовременная тактика лечения опухолевых перикардитовModern tactics of treatment of tumor pericarditisТитовК. С.TitovK. S.

д. м. н., заведующий онкохирургическим отделением опухолей кожи и мягких тканей ГБУЗ «Московский клинический научно-практический центр им. А.С. Логинова» Департамента здравоохранения г. Москвы, доцент кафедры онкологии и лучевой терапии лечебного факультета «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава РФ

MD, PhD, Head of the Оnсоsurgery Department of Tumors of Skin and Soft Tissues, Moscow Clinical Scientific Center; Associate Professor of the Department of Oncology and Radiation Therapy of the Faculty of Medicine, N.I. Pirogov Russian National Research Medical University

ks-titov@mail.ruКиселевскийМ. В.KiselevskM. V.

д. м. н., профессор, заслуженный деятель науки РФ, заведующий лабораторией клеточного иммунитета НИИ Экспериментальной диагностики и терапии опухолей ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава РФ

MD, PhD, Professor, Head of the Laboratory of Cellular Immunity

kisele@inbox.ruГБУЗ «Московский клинический научно-практический центр» ДЗ г. Москвы; «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава РФРоссияMoscow Clinical Scientific Center; N.I. Pirogov Russian National Research Medical UniversityRussian FederationФГБУ «Национальный медицинский исследовательский центр онкологии им. Н. Н. Блохина» Минздрава РФРоссияN. N. Blokhin Russian Cancer Research CenterRussian Federation201717112017035761Copyright © Титов К.С., Киселевский М.В., 20172017Титов К.С., Киселевский М.В.Titov K.S., Kiselevsk M.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.malignanttumors.org/jour/article/view/392

Опухолевый перикардит у онкологических больных развивается на поздних стадиях и в 95 % случаев обусловлен метастазами при раке легкого, при раке молочной железы, при гемобластозах и при раке органов желудочно-кишечного тракта. Злокачественный выпот в полости перикарда в половине случаев приводит к тампонаде сердца и смерти больного. На сегодняшний день в онкологии актуальной задачей является поиск оптимально эффективного и низкотоксичного лечения канцероматоза перикарда и опухолевого перикардита. Одним из эффективных методов лечения данной сложной категории онкологических больных является внутриперикардиальная ИЛ-2-иммунотерапия.

 

 

 

 

Pericarditis in cancer patients occures in the late stage of the disease and in 95% of cases is caused by metastases of lung, breast, gastrointestinal cancer and hemoblastosis. Malignant exudate in the pericardial cavity in half cases leads to tamponade of the heart and death of the patient. The actual goal in modern oncology is to find the most effective and low-toxic treatment of pericardial carcinomatosis and tumor pericarditis. One of the effective methods of treating of this category of patients is intrapericardial immunotherapy with IL-2.

 

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The authors declare that there are no conflicts of interest present.