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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">tumors</journal-id><journal-title-group><journal-title xml:lang="ru">Malignant tumours</journal-title><trans-title-group xml:lang="en"><trans-title>Malignant tumours</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2224-5057</issn><issn pub-type="epub">2587-6813</issn><publisher><publisher-name>Rosoncoweb</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18027/2224-5057-2017-1-30-36</article-id><article-id custom-type="elpub" pub-id-type="custom">tumors-324</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL REPORTS</subject></subj-group></article-categories><title-group><article-title>Реконструкция молочной железы и лучевая терапия</article-title><trans-title-group xml:lang="en"><trans-title>Breast reconstruction and radiotherapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ЗЕРНОВ</surname><given-names>К. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>ZERNOV</surname><given-names>K. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м.н., научный сотрудник отделения опухолей молочной железы</p></bio><bio xml:lang="en"><p>MD, PhD, researcher of breast cancer department</p></bio><email xlink:type="simple">konstantin_zernov@hotmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ДАШЯН</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>DASHYAN</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м.н., ведущий научный сотрудник отделения опухолей молочной железы</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, leading researcher of breast cancer department</p></bio><email xlink:type="simple">dgarik@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>КРИВОРОТЬКО</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>KRIVOROTKO</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м.н., зав. отделением опухолей молочной железы</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, head of breast cancer department</p></bio><email xlink:type="simple">dr.krivorotko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>НОВИКОВ</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>NOVIKOV</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м.н., заведующий отделением лучевой терапии</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, head of radiotherapy department</p></bio><email xlink:type="simple">krokon@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ПАЛТУЕВ</surname><given-names>Р. М.</given-names></name><name name-style="western" xml:lang="en"><surname>PALTUEV</surname><given-names>R. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м.н., научный сотрудник отделения опухолей молочной железы</p></bio><bio xml:lang="en"><p>MD, PhD, researcher of breast cancer department</p></bio><email xlink:type="simple">paltuev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ТАБАГУА</surname><given-names>Т. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>TABAGUA</surname><given-names>T. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м.н., научный сотрудник отделения опухолей молочной железы</p></bio><bio xml:lang="en"><p>MD, PhD, researcher of breast cancer department,</p></bio><email xlink:type="simple">tedo8308@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ЖИЛЬЦОВА</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>ZHILTSOVA</surname><given-names>E. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м.н., врач отделения опухолей молочной железы</p></bio><bio xml:lang="en"><p>MD, Ph, researcher of breast cancer department</p></bio><email xlink:type="simple">ziltsova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ОПЕРМАНАС</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>OPERMANAS</surname><given-names>Y. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>клинический ординатор кафедры онкологии</p></bio><bio xml:lang="en"><p>resident</p></bio><email xlink:type="simple">opjurij@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ЕМЕЛЬЯНОВ</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>EMELIANOV</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>клинический ординатор</p></bio><bio xml:lang="en"><p>resident</p></bio><email xlink:type="simple">ae28111992@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ЕРЕЩЕНКО</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>ERESHENKO</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>клинический ординатор</p></bio><bio xml:lang="en"><p>resident</p></bio><email xlink:type="simple">seriy_1111@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ПЕТРОВА</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>PETROVA</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>клинический ординатор</p></bio><bio xml:lang="en"><p>resident</p></bio><email xlink:type="simple">avpetrova91@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>КАНАЕВ</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>KANAEV</surname><given-names>S. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>СЕМИГЛАЗОВ</surname><given-names>В. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>SEMIGLAZOV</surname><given-names>V. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>член-корр. РАН, профессор, заведующий отдела опухолей репродуктивной системы и научным отделением опухолей молочной железы</p></bio><bio xml:lang="en"><p>MD, PhD, DSc, professor head of reproductive cancer department</p></bio><email xlink:type="simple">ssemiglazov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НИИ онкологии им. Н. Н. Петрова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budget Institution «Research Oncology Institute named after N. N. Petrov» Ministry of Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБОУ ВПО ПСПбГМУ им. акад. И. П. Павлова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budget Institution «Pavlov First Saint Petersburg State Medical&#13;
University» Ministry of Health</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>04</day><month>07</month><year>2017</year></pub-date><volume>0</volume><issue>1</issue><fpage>30</fpage><lpage>36</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; ЗЕРНОВ К.Ю., ДАШЯН Г.А., КРИВОРОТЬКО П.В., НОВИКОВ С.Н., ПАЛТУЕВ Р.М., ТАБАГУА Т.Т., ЖИЛЬЦОВА Е.К., ОПЕРМАНАС Ю.А., ЕМЕЛЬЯНОВ А.С., ЕРЕЩЕНКО С.С., ПЕТРОВА А.П., КАНАЕВ С.В., СЕМИГЛАЗОВ В.Ф., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">ЗЕРНОВ К.Ю., ДАШЯН Г.А., КРИВОРОТЬКО П.В., НОВИКОВ С.Н., ПАЛТУЕВ Р.М., ТАБАГУА Т.Т., ЖИЛЬЦОВА Е.К., ОПЕРМАНАС Ю.А., ЕМЕЛЬЯНОВ А.С., ЕРЕЩЕНКО С.С., ПЕТРОВА А.П., КАНАЕВ С.В., СЕМИГЛАЗОВ В.Ф.</copyright-holder><copyright-holder xml:lang="en">ZERNOV K.Y., DASHYAN G.A., KRIVOROTKO P.V., NOVIKOV S.N., PALTUEV R.M., TABAGUA T.T., ZHILTSOVA E.K., OPERMANAS Y.A., EMELIANOV A.S., ERESHENKO S.S., PETROVA A.P., KANAEV S.V., SEMIGLAZOV V.F.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.malignanttumors.org/jour/article/view/324">https://www.malignanttumors.org/jour/article/view/324</self-uri><abstract><p>В последние годы отмечаются значительные продвижения в области ауто- и гетерологических реконструкций молочных желез. Реконструкция с помощью имплантатов при мастэктомии используется все чаще. Недавнее исследование, проведенное Albronoz с соавторами, на основе данных Nationwide Inpatient Sample с 1998 по 2008 год, выявило увеличение частоты одномоментных реконструкций имплантатами в среднем на 11% в год, по сравнению с аутологичными методами реконструкции [Barreau-Pouhaer L., 1992]. Возможной причиной для этого увеличения является растущее число молодых, нуждающихся в мастэктомии и не располагающих достаточной жировой клетчаткой для аутологичной реконструкции. Цель реконструкции – достичь долгосрочного, безопасного с онкологических позиций и эстетически удовлетворительного результата с рациональными затратами на операцию. Лучевая терапия после мастэктомии, как часть комплексного лечения, требуется все большему числу больных при раке молочной железы. Она, хотя и  является важнейшим  компонентом в лечении рака молочной железы, связана с высокой частотой возникновения осложнений. Следует надлежащим образом консультировать пациентово возможности этих потенциальных осложнений, с тем, чтобы они могли принимать обоснованные решения.</p></abstract><trans-abstract xml:lang="en"><p>In recent years there were significant advances in auto- and heterological breast reconstruction. Reconstruction with implants after mastectomy is being used more of ten. A recent study conducted by Albronoz et al, based on Nationwide Inpatient Sample data, found an increasing rate of immediate breast reconstruction with implants af ter mastectomy up to 11%, compared to autological methods of reconstruction [Barreau-Pouhaer L., 1992]. A possible reason for this increase is the growing number of young patients who need a mastectomy, but have not enough fat tissue for autological reconstruction. The purpose of reconstruction is to reach a long-term, oncologically safe and aesthetically pleasing result with reasonable operation expenses. Radiation therapy after mastectomy, as part of a complex treatment, is needed for an increasing amount of patients with breast cancer. Radiation therapy is a vital par t of cancer treatment, but often causes complications. Patients should be informed and consulted about potential complications so they can make reasonable decisions about their treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>реконструкция</kwd><kwd>лучевая терапия</kwd><kwd>осложнения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>reconstruction</kwd><kwd>radiotherapy</kwd><kwd>complications</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">ASPS (American Society of Plastic Surgeons): Evidencebased clinicalpractice guideline: Breast reconstruction with expanders and implants. www.plasticsurgery.org/ reconstructive-procedures/ breast-reconstruction.html; 2013 (last accessed on 1 July 2015).</mixed-citation><mixed-citation xml:lang="en">ASPS (American Society of Plastic Surgeons): Evidencebased clinicalpractice guideline: Breast reconstruction with expanders and implants. www.plasticsurgery.org/ reconstructive-procedures/ breast-reconstruction.html; 2013 (last accessed on 1 July 2015).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Albornoz C.R., Bach P.B., Mehrara B.J. et al. 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