<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">tumors</journal-id><journal-title-group><journal-title xml:lang="ru">Malignant tumours</journal-title><trans-title-group xml:lang="en"><trans-title>Malignant tumours</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2224-5057</issn><issn pub-type="epub">2587-6813</issn><publisher><publisher-name>Rosoncoweb</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18027/2224-5057-2016-4-41-47</article-id><article-id custom-type="elpub" pub-id-type="custom">tumors-271</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL REPORTS</subject></subj-group></article-categories><title-group><article-title>ЛАПАРОСКОПИЧЕСКАЯ ЭКСТИРПАЦИЯ МАТКИ С ТАЗОВОЙ ЛИМФАДЕНЭКТОМИЕЙ КАК АЛЬТЕРНАТИВА ЛАПАРОТОМИИ ПРИ ЛЕЧЕНИИ РАКА ЭНДОМЕТРИЯ</article-title><trans-title-group xml:lang="en"><trans-title>LAPAROSCOPIC HUSTERECTOMY  WITH A PELVIC LYMPHADENECTOMY, AS ALTERNATIVE LAPAROTOMY AT ENDOMETRIUM CANCER  SURGERY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анпилогов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Anpilogov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анпилогов Сергей Владимирович – кандидат медицинских наук, научный сотрудник отделения гинекологии МНИОИ имени П. А. Герцена, Москва</p></bio><bio xml:lang="en"/><email xlink:type="simple">ann0071@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шевчук</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shevchuk</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шевчук Алексей Сергеевич – кандидат медицинских наук, ведущий научный сотрудник отделения гинекологии МНИОИ имени П. А. Герцена, Москва</p></bio><bio xml:lang="en"><p>Shevchuk Alexey Sergeyevich – MD, PhD, leading researcher of office of gynecology MNIOI P. A. Herzen,  Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новикова</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Novikova</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Новикова Елена Григорьевна – доктор медицинских наук, профессор, руководитель отделения гинекологии МНИОИ имени П. А. Герцена, Москва</p></bio><bio xml:lang="en"><p>Novikova Elena Grigoryevna – MD, PhD, DSc, Professor, the head of office of gynecology MNIOI P. A. Herzen,  Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский научно-исследовательский онкологический институт имени П. А. Герцена</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Р. Hertsen Moscow Oncology Research Institute - Branch of the National Medical Research Radiological Centre of the Ministry Of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>16</day><month>11</month><year>2016</year></pub-date><volume>0</volume><issue>4</issue><fpage>41</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Анпилогов С.В., Шевчук А.С., Новикова Е.Г., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Анпилогов С.В., Шевчук А.С., Новикова Е.Г.</copyright-holder><copyright-holder xml:lang="en">Anpilogov S.V., Shevchuk A.S., Novikova E.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.malignanttumors.org/jour/article/view/271">https://www.malignanttumors.org/jour/article/view/271</self-uri><abstract><p>В гинекологическом  отделении онкологического института имени П. А. Герцена с июля 2010 г. по декабрь 2015 г. лапароскопическая гистерэктомия с тазовой лимфаденэктомией по поводу рака эндометрия I стадии выполнена у 210 женщин. Техника операции модифицирована в соответствии с онкологическими  требованиями.  С целью увеличения абластичности операции до установки маточного манипулятора пересекались основные сосуды, участвующие в кровоснабжении матки.</p><p>Средний возраст всех пациенток составил 55±11,5 лет. Более половины (64%) пациенток имели избыточную массу тела, либо ожирение (медиана ИМТ = 27). Продолжительность операции варьировала от 105 до 305 минут, в среднем составила 167,3±43,1, медиана 173 минуты. Средняя кровопотеря составила 95 мл (медиана 65 мл). В ложе удаленных лимфоузлов  у 37,1% больных (N=78) отмечено формирование  лимфатических кист. Общая продолжительность пребывания в стационаре составила 9,8±2,8 койко-дней, после операции – 6,9±1,7 дней. Таким образом, послеоперационный период характеризовался в целом гладким течением и минимальным числом осложнений.</p><p>Лапароскопическая экстирпация матки с тазовой лимфаденэктомией может рассматриваться в качестве безопасной альтернативы классическим лапаротомным методикам.</p></abstract><trans-abstract xml:lang="en"><p>In gynecology department  of oncologic institute of P. A. Herzen from July, 2010 to December, 2015, the laparoscopic hysterectomy with a pelvic lymphadenectomy concerning endometrial cancer of the I stage is executed at 210 women. Technology of operation is modified according to oncologic demands. Before installation of the uterine manipulator the main vessels participating in blood supply of a uterus for an operation ablastichnost were alloyed.</p><p>Average age of all patients made 55 ± 11,5 years. More than a half (64%) of patients had the excess body weight, or an obesity (BMI median  = 27). Duration of operation varied from 105 to 305 minutes, averaged 167,3±43,1, a median 173 minutes. An average hemorrhage  made 95 ml (a median of 65 ml). At 37,1% of patients  (N=78) formation of lymphatic cysts is noted. The general duration of stay in a hospital made 9,8 ± 2,8 days, after operation – 6,9 ± 1,7 days. Thus, the postoperative period was characterized in general by a smooth current and the minimum of complications.</p><p>The laparoscopic hysterectomy with a pelvic lymphadenectomy can be considered as a safe alternative to classical laparotomy techniques. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>лапароскопическая экстирпация матки с тазовой лимфаденэктомией</kwd><kwd>рак эндометрия</kwd><kwd>маточный манипулятор</kwd></kwd-group><kwd-group xml:lang="en"><kwd>the laparoscopic hysterectomy with a pelvic lymphadenectomy</kwd><kwd>endometrial cancer</kwd><kwd>the uterine manipulator</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Берлев И. В., Урманчеева А. Ф., Максимов С. Я., Некрасова Е. А. Сравнительный анализ хирургического лечения рака эндометрия лапароскопическим и традиционным лапаротомным доступами /Сибирский онкологический журнал 2012; 6 (54): 32-36. Berlev I. V., Urmancheeva A. F., Maximov S. Ya., Nekrasova E. A. The comparative analysis of surgical cancer therapy of endometrium laparoscopic and traditional laparotomny accesses / the Siberian oncological magazine 2012; 6 (54): 32-36.</mixed-citation><mixed-citation xml:lang="en">Берлев И. В., Урманчеева А. Ф., Максимов С. Я., Некрасова Е. А. Сравнительный анализ хирургического лечения рака эндометрия лапароскопическим и традиционным лапаротомным доступами /Сибирский онкологический журнал 2012; 6 (54): 32-36. Berlev I. V., Urmancheeva A. F., Maximov S. Ya., Nekrasova E. A. The comparative analysis of surgical cancer therapy of endometrium laparoscopic and traditional laparotomny accesses / the Siberian oncological magazine 2012; 6 (54): 32-36.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Каприн А. Д., Старинский В. В., Петрова Г. В. Состояние онкологической помощи населению России в 2014 году, Москва 2015, с. 18. Kaprin A.D., Starinsky V.V., Petrov of G.V. Sostoyaniye of the oncological help to the population of Russia in 2014, Moscow 2015, with 18.</mixed-citation><mixed-citation xml:lang="en">Каприн А. Д., Старинский В. В., Петрова Г. В. Состояние онкологической помощи населению России в 2014 году, Москва 2015, с. 18. Kaprin A.D., Starinsky V.V., Petrov of G.V. Sostoyaniye of the oncological help to the population of Russia in 2014, Moscow 2015, with 18.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Каприн А. Д., Старинский В. В., Петрова Г. В. Состояние онкологической помощи населению России в 2014 году, 8. Москва 2015, с. 25. Kaprin A. D., Starinsky V. V., Petrov of G. V. Sostoyaniye of the oncological help to the population of Russia in 2014, Moscow 2015, with 25.</mixed-citation><mixed-citation xml:lang="en">Каприн А. Д., Старинский В. В., Петрова Г. В. Состояние онкологической помощи населению России в 2014 году, 8. Москва 2015, с. 25. Kaprin A. D., Starinsky V. V., Petrov of G. V. Sostoyaniye of the oncological help to the population of Russia in 2014, Moscow 2015, with 25.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Bige 0., Demir A., Saatli B., Koyuncuojjlu M., Saygili U. Laparoscopy versus laparotomy for the management of endometrial carcinoma in morbidly obese patients: a prospective study. J Turk Ger Gynecol Assoc. 2015 Jul 14;16(3):164-9.</mixed-citation><mixed-citation xml:lang="en">Bige 0., Demir A., Saatli B., Koyuncuojjlu M., Saygili U. Laparoscopy versus laparotomy for the management of endometrial carcinoma in morbidly obese patients: a prospective study. J Turk Ger Gynecol Assoc. 2015 Jul 14;16(3):164-9.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Farthing A., Chatterjee J., Joglekar-Pai P., Dorney E., Ghaem-Maghami S. Total laparoscopic hysterectomy for early stage EC in obese and morbidly obese women. J Obstet Gynaecol. 2012;32:580-4.</mixed-citation><mixed-citation xml:lang="en">Farthing A., Chatterjee J., Joglekar-Pai P., Dorney E., Ghaem-Maghami S. Total laparoscopic hysterectomy for early stage EC in obese and morbidly obese women. J Obstet Gynaecol. 2012;32:580-4.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Gamal H. E., Uterine Manipulation in Laparoscopic Hysterectomy / The Female Patient 2010 Sep; 35:18-23.</mixed-citation><mixed-citation xml:lang="en">Gamal H. E., Uterine Manipulation in Laparoscopic Hysterectomy / The Female Patient 2010 Sep; 35:18-23.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Gao H., Zhang Z. Laparoscopy Versus Laparotomy in the Treatment of High-Risk Endometrial Cancer: A Propensity Score Matching Analysis. Medicine (Baltimore). 2015 Jul;94(30).</mixed-citation><mixed-citation xml:lang="en">Gao H., Zhang Z. Laparoscopy Versus Laparotomy in the Treatment of High-Risk Endometrial Cancer: A Propensity Score Matching Analysis. Medicine (Baltimore). 2015 Jul;94(30).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Helm C. W., Arumugam C., Gordinier M. E., Metzinger D. S., Pan J., Rai S. N. Laparoscopic surgery for EC: increasing body mass index does not impact postoperative complications. J Gynecol Oncol. 2011;22:168–76.</mixed-citation><mixed-citation xml:lang="en">Helm C. W., Arumugam C., Gordinier M. E., Metzinger D. S., Pan J., Rai S. N. Laparoscopic surgery for EC: increasing body mass index does not impact postoperative complications. J Gynecol Oncol. 2011;22:168–76.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Herling S. F., Palle C., M ller A. M., Thomsen T., S rensen J. Cost analysis of robotic-assisted laparoscopic hysterectomy versus total abdominal hysterectomy for women with endometrial cancer and atypical complex hyperplasia. Acta Obstet Gynecol Scand. 2015 Nov 17.</mixed-citation><mixed-citation xml:lang="en">Herling S. F., Palle C., M ller A. M., Thomsen T., S rensen J. Cost analysis of robotic-assisted laparoscopic hysterectomy versus total abdominal hysterectomy for women with endometrial cancer and atypical complex hyperplasia. Acta Obstet Gynecol Scand. 2015 Nov 17.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Juhasz-B ss I., Mallmann P., M ller C. P., Solomayer E. F. Use of Laparoscopy in the Treatment of Endometrial and Cervical Cancer – Results of a 2012 Germany-wide Survey. Geburtshilfe Frauenheilkd. 2013 Sep;73(9):911–917.</mixed-citation><mixed-citation xml:lang="en">Juhasz-B ss I., Mallmann P., M ller C. P., Solomayer E. F. Use of Laparoscopy in the Treatment of Endometrial and Cervical Cancer – Results of a 2012 Germany-wide Survey. Geburtshilfe Frauenheilkd. 2013 Sep;73(9):911–917.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Machida H., Casey J. P., Garcia-Sayre J., Jung C. E., Casabar J. K., Moeini A., Kato K., Roman L. D., Matsuo K. Timing of Intrauterine Manipulator Insertion During Minimally Invasive Surgical Staging and Results of Pelvic Cytology in Endometrial Cancer. J Minim Invasive Gynecol. 2015 Oct 22. pii: S1553–650(15)01620–9.</mixed-citation><mixed-citation xml:lang="en">Machida H., Casey J. P., Garcia-Sayre J., Jung C. E., Casabar J. K., Moeini A., Kato K., Roman L. D., Matsuo K. Timing of Intrauterine Manipulator Insertion During Minimally Invasive Surgical Staging and Results of Pelvic Cytology in Endometrial Cancer. J Minim Invasive Gynecol. 2015 Oct 22. pii: S1553–650(15)01620–9.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Martinek I., Haldar K., Tozzi R. Laparoscopic surgery for gynaecological cancers in obese women.Maturitas. 2010;65:320–4.</mixed-citation><mixed-citation xml:lang="en">Martinek I., Haldar K., Tozzi R. Laparoscopic surgery for gynaecological cancers in obese women.Maturitas. 2010;65:320–4.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Obermair A., Manolitsas T. P., Leung Y., Hammond I. G., McCartney A. J. Total laparoscopic hysterectomy versus total abdominal hysterectomy for obese women with EC. Int J Gynaecol Cancer. 2005;15:319–24.</mixed-citation><mixed-citation xml:lang="en">Obermair A., Manolitsas T. P., Leung Y., Hammond I. G., McCartney A. J. Total laparoscopic hysterectomy versus total abdominal hysterectomy for obese women with EC. Int J Gynaecol Cancer. 2005;15:319–24.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">zg r Bige, Ahmet Demir, Bahadir Saatli, Meral Koyuncuo lu, and U ur Saygili. Laparoscopy versus laparotomy for the management of endometrial carcinoma in morbidly obese patients: a prospective study. J Turk Ger Gynecol Assoc. 2015; 16(3): 164–169.</mixed-citation><mixed-citation xml:lang="en">zg r Bige, Ahmet Demir, Bahadir Saatli, Meral Koyuncuo lu, and U ur Saygili. Laparoscopy versus laparotomy for the management of endometrial carcinoma in morbidly obese patients: a prospective study. J Turk Ger Gynecol Assoc. 2015; 16(3): 164–169.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Parker V. L., Sanderson P, Raw D., Farag K. Eur J Gynaecol Oncol. 2015;36(5):595–8. Do we understand the pathophysiology of endometrial cancer?</mixed-citation><mixed-citation xml:lang="en">Parker V. L., Sanderson P, Raw D., Farag K. Eur J Gynaecol Oncol. 2015;36(5):595–8. Do we understand the pathophysiology of endometrial cancer?</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Park D. Clinical Effectiveness And Safety Of Robot-Assisted Laparoscopic Hysterectomy Versus Traditional Laparotomy For Endometrial Cancer: A Systematic Review. Value Health. 2015 Nov;18(7): A433.</mixed-citation><mixed-citation xml:lang="en">Park D. Clinical Effectiveness And Safety Of Robot-Assisted Laparoscopic Hysterectomy Versus Traditional Laparotomy For Endometrial Cancer: A Systematic Review. Value Health. 2015 Nov;18(7): A433.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Paw owicz P., Czeka ska M., Rawski W. et al. Laparoscopic excision of pelvic lymphs nodes after vaginal hysterectomy due to histological blunder. Case report of two patients. Prz Menopauz. 2011;5:383–5.</mixed-citation><mixed-citation xml:lang="en">Paw owicz P., Czeka ska M., Rawski W. et al. Laparoscopic excision of pelvic lymphs nodes after vaginal hysterectomy due to histological blunder. Case report of two patients. Prz Menopauz. 2011;5:383–5.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Paw owicz, Pawe S.; Ajdacka, Urszula. Videosurgery &amp; Other Miniinvasive Techniques / Wideochirurgia i Inne Techniki Malo Inwazyjne. Mar2015, Vol. 10 Issue 1, p44–48.</mixed-citation><mixed-citation xml:lang="en">Paw owicz, Pawe S.; Ajdacka, Urszula. Videosurgery &amp; Other Miniinvasive Techniques / Wideochirurgia i Inne Techniki Malo Inwazyjne. Mar2015, Vol. 10 Issue 1, p44–48.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Soliman H. O., Elsebaie H. I., Gad Z. S., Iskandar S. S., Gareer W. Y. Laparoscopic hysterectomy in the treatment of endometrial cancer: NCI experience. J Egypt Natl Canc Inst. 2011 Sep;23(3):101–4. doi: 10.1016/j.jnci.2011.09.008. Epub 2011 Oct 21.</mixed-citation><mixed-citation xml:lang="en">Soliman H. O., Elsebaie H. I., Gad Z. S., Iskandar S. S., Gareer W. Y. Laparoscopic hysterectomy in the treatment of endometrial cancer: NCI experience. J Egypt Natl Canc Inst. 2011 Sep;23(3):101–4. doi: 10.1016/j.jnci.2011.09.008. Epub 2011 Oct 21.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Sonoda Y., Barakat R. R. Screening and prevention of gynecologic cancer: endometrial cancer. Res Clin Obstet Gyn. 2006;20:363–77.</mixed-citation><mixed-citation xml:lang="en">Sonoda Y., Barakat R. R. Screening and prevention of gynecologic cancer: endometrial cancer. Res Clin Obstet Gyn. 2006;20:363–77.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Surynt E., Reinholz-Jaskolska M., Bidzinski M. Laparoscopic sentinel lymph node mapping after cervical injection of indocyanine green for endometrial cancer – preliminary report. Wideochir Inne Tech Maloinwazyjne. 2015 Sep;10(3):406–12.</mixed-citation><mixed-citation xml:lang="en">Surynt E., Reinholz-Jaskolska M., Bidzinski M. Laparoscopic sentinel lymph node mapping after cervical injection of indocyanine green for endometrial cancer – preliminary report. Wideochir Inne Tech Maloinwazyjne. 2015 Sep;10(3):406–12.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
