tumorsMalignant tumoursMalignant tumours2224-50572587-6813Rosoncoweb10.18027/2224-5057-2016-2-43-48tumors-232Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL REPORTSПероральная форма винорелбина в монотерапии распространенного рака молочной железы. Обзор литературыOral vinorelbine as monotherapy in treatment of advanced breast cancer. Literature reviewХисамовАртур АльбертовичKhisamovArthur A.

врач-хирург

surgeon

a.khisamov@mknc.ruГБУЗ МКНЦ ДЗМРоссияMoscow Clinical Scientific CenterRussian Federation201602082016024348Copyright © Хисамов А.А., 20162016Хисамов А.А.Khisamov A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.malignanttumors.org/jour/article/view/232

Целью лечения распространенного рака молочной железы (РМЖ), помимо увеличения продолжительности жизни и увеличения длительности ремиссии, является улучшение качества жизни пациентов. На сегодняшний день определяющим в лечении пациентов с распространенным раком молочной железы является биологический подтип опухоли, а подход к выбору препаратов должен быть индивидуальным и учитывать множество факторов, включая длительность жизни без прогрессирования, уже проводившееся лечение, биологию опухоли, наличие висцеральных метастазов, характер сопутствующей патологии и пожелания пациента [1]. Все эти факторы необходимо учитывать при обсуждении вариантов последующей химиотерапии у больных с прогрессированием болезни после антрациклинов и/или таксанов.

The aim of the treatment of advanced breast cancer, in addition to increasing of overall survival and increasing of the duration of remission, is to improve the quality of life of such patients. To date, the determining factor in the treatment of patients with advanced breast cancer is a biological type of the tumor, and the approach to the choice of chemotherapy should be individualized taking into account many factors, including the duration of progression-free survival, already provided treatment, the biology of the tumor, presence of visceral metastases, the nature of comorbidity and the patient’s wishes. All these factors need to be considered when discussing the options for subsequent chemotherapy in patients with disease progression after anthracyclines and/or taxanes.

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The authors declare that there are no conflicts of interest present.