tumorsMalignant tumoursMalignant tumours2224-50572587-6813Rosoncoweb10.18027/2224-5057-2012-2-6-11tumors-21Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL REPORTSНЕОАДЪЮВАНТНАЯ ТЕРАПИЯ ГОРМОНОЗАВИСИМОГО РАКА МОЛОЧНОЙ ЖЕЛЕЗЫСемиглазовВ. Ф.СемиглазовВ. В.МанихасА. Г.ДашянГ. А.ИвановВ. Г.СемиглазоваТ. Ю.ПалтуевР. М.ФГБУ «НИИ онкологии им. Н.Н. Петрова» Минздравсоцразвития России, Санкт-ПетербургRussian FederationСанкт-Петербургский Государственный Медицинский Университет им. акад. И.П. Павлова, Санкт-ПетербургRussian FederationСПб ГУЗ «Городской клинический онкологический диспансер» , Санкт-ПетербургRussian Federation20122005201522611Copyright © Семиглазов В.Ф., Семиглазов В.В., Манихас А.Г., Дашян Г.А., Иванов В.Г., Семиглазова Т.Ю., Палтуев Р.М., 20152015Семиглазов В.Ф., Семиглазов В.В., Манихас А.Г., Дашян Г.А., Иванов В.Г., Семиглазова Т.Ю., Палтуев Р.М.Семиглазов В.Ф., Семиглазов В.В., Манихас А.Г., Дашян Г.А., Иванов В.Г., Семиглазова Т.Ю., Палтуев Р.М.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.malignanttumors.org/jour/article/view/21

Относительно недавно неоадъювантная эндокринотерапия стала рассматриваться как привлекательная альтернатива химиотерапевтическому лечению у постменопаузальных пациенток с крупными или неоперабельными ЭР-положительными опухолями. И хотя на сегодняшний день не было проведено крупных рандомизированных исследований, сравнивающих результаты только хирургического лечения и неоадьювантной эндокринотерапии с последующим хирургическим вмешательством, ряд исследований ингибиторов ароматазы (ИА) продемонстрировал обнадеживающие результаты. В нескольких крупных исследованиях проводилось сравнение различных ингибиторов ароматазы и тамоксифена. Одним из основных конечных результатов, по которым проводилась оценка эффективности лечения, являлась частота выполнения органосохраняюшего лечения.

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The authors declare that there are no conflicts of interest present.