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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">tumors</journal-id><journal-title-group><journal-title xml:lang="ru">Malignant tumours</journal-title><trans-title-group xml:lang="en"><trans-title>Malignant tumours</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2224-5057</issn><issn pub-type="epub">2587-6813</issn><publisher><publisher-name>Rosoncoweb</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18027/2224-5057-2025-15-3s1-38-46</article-id><article-id custom-type="elpub" pub-id-type="custom">tumors-1504</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Пути повышения эффективности лечения местно-распространенных и метастатических форм злокачественных опухолей желудка на современном этапе</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2306-8959</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сельчук</surname><given-names>В. Ю.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимир Юрьевич Сельчук</p><p>127006 Москва, ул. Долгоруковская, 4</p><p> </p></bio><email xlink:type="simple">selvu@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-0908-2831</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кочоян</surname><given-names>Т. М.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кочоян Теймураз Мразович</p><p>127006 Москва, ул. Долгоруковская, 4</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-1861-3306</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гребенникова</surname><given-names>О. П.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гребенникова Ольга Петровна</p><p>127006 Москва, ул. Долгоруковская, 4</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2017-6324</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Емельянова</surname><given-names>Г. С.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Емельянова Галина Сергеевна</p><p>127006 Москва, ул. Долгоруковская, 4</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5927-8096</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таджибов</surname><given-names>С. Н.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Таджибов Сабир Надирович</p><p>127006 Москва, ул. Долгоруковская, 4</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6878-2972</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Титова</surname><given-names>Г. В.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Титова Галина Владимировна</p><p>127006 Москва, ул. Долгоруковская, 4</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБОУ ВО «Российский университет медицины» Минздрава России</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>11</month><year>2025</year></pub-date><volume>15</volume><issue>3s1</issue><fpage>38</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сельчук В.Ю., Кочоян Т.М., Гребенникова О.П., Емельянова Г.С., Таджибов С.Н., Титова Г.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Сельчук В.Ю., Кочоян Т.М., Гребенникова О.П., Емельянова Г.С., Таджибов С.Н., Титова Г.В.</copyright-holder><copyright-holder xml:lang="en">Сельчук В.Ю., Кочоян Т.М., Гребенникова О.П., Емельянова Г.С., Таджибов С.Н., Титова Г.В.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.malignanttumors.org/jour/article/view/1504">https://www.malignanttumors.org/jour/article/view/1504</self-uri><abstract><p>Тезисы: Диагностика ранних форм рака желудка (I–II стадии) остаётся на невысоком уровне. Большинство больных выявляются в запущенных (III–IV) стадиях. Лечение местнораспространенного и метастатического рака желудка неудовлетворительно и требует своего улучшения. Наряду с совершенствованием комбинированного хирургического лечения открытым лапаротомным доступом предпринимаются попытки лапароскопических вмешательств по поводу местнораспространенного рака желудка. В лечении также рассматривается обзор системной химиотерапии метастатического рака желудка, циторедуктивной хирургии, паллиативной внутрибрюшной химиотерапии, внутрибрюшной аэрозольной химиотерапии под давлением (PIPAC).</p></abstract><kwd-group xml:lang="ru"><kwd>местнораспространенный и метастатический рак желудка</kwd><kwd>канцероматоз брюшины</kwd><kwd>профилактика</kwd><kwd>диагностика и лечение</kwd><kwd>хирургия</kwd><kwd>химиотерапия</kwd><kwd>HIPEC</kwd><kwd>PIPAC</kwd><kwd>лучевая терапия</kwd><kwd>иммунотерапия</kwd><kwd>молекулярные классификации рака желудка</kwd><kwd>перспективы исследований</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Каприн А.Д. и соавт. «Злокачественные новообразования в России в 2023 году (заболеваемость и смертность)» Москва 2025 г.</mixed-citation><mixed-citation xml:lang="en">Каприн А.Д. и соавт. «Злокачественные новообразования в России в 2023 году (заболеваемость и смертность)» Москва 2025 г.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Бесова Н.С., Болотина Л.В., Гамаюнов С.В., и соавт. 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