tumorsMalignant tumoursMalignant tumours2224-50572587-6813Rosoncoweb10.18027/2224-5057-2025-053tumors-1497Research ArticleКОНСЕНСУСCONSENSUSРоссийский консенсус по профилактике, диагностике и лечению рака желудка. Вопросы профилактики, ранней диагностики, предраковых заболеванийRussian consensus on prevention, diagnostics and treatment of gastric cancer. Issues of prevention, early diagnostics, and precancerous diseaseshttps://orcid.org/0000-0001-9542-3580АбдулхаковС. Р.AbdulkhakovS. R.

Абдулхаков Сайяр Рустамович 

420008 Казань, Кремлевская ул., 18, корп. 1

Abdulkhakov Sayyar Rustamovich

Build 1, 18 Kremlevskaya St., Kazan 420008

https://orcid.org/0000-0003-1724-9980АлексеенкоС. А.AlekseenkoS. A.

Алексеенко Сергей Алексеевич 

680000 Хабаровск, Муравьева-Амурского ул., 35

Alekseenko Sergey Alekseevich

35 St., Khabarovsk 680000

https://orcid.org/0000-0002-4007-7112АндреевД. Н.AndreevD. N.

Андреев Дмитрий Николаевич 

127473 Москва, ул. Делегатская, 20, стр. 1 

Andreev Dmitry Nikolaevich

Build. 1, 20 Delegatskaya St., Moscow 127473

https://orcid.org/0000-0003-4075-4096БакулинаН. В.BakulinaN. V.

Бакулина Наталья Валерьевна 

191015 Санкт-Петербург, ул. Кирочная, 41 

Bakulina Natalya Valerievna

41 Kirochnaya St., Saint Petersburg 191015

https://orcid.org/0000-0003-2815-3992БординД. С.BordinD. S.

Бордин Дмитрий Станиславович 

111123 Москва, Новогиреевская ул., 1, корп. 1 

Bordin Dmitry Stanislavovich

Build. 1, 1 Novogireevskaya St., Moscow 111123

https://orcid.org/0000-0001-7254-5411ИзраиловР. Е.IzrailovR. E.

Израилов Роман Евгеньевич 

111123 Москва, Новогиреевская ул., 1, корп. 1 

Izrailov Roman Evgenievich

Build. 1, 1 Novogireevskaya St., Moscow 111123

https://orcid.org/0000-0002-4417-8076ИсаковВ. А.IsakovV. A.

Исаков Василий Андреевич 

109240 Москва, Устьинский проезд, 2 / 14

Isakov Vasily Andreevich

2/14 Ustinsky Pr., Moscow 109240

КуриловичС. А.KurilovichS. A.

630089 Новосибирск, ул. Бориса Богаткова, 175 / 1 

175/1 Bogatkova St., Novosibirsk 630089

https://orcid.org/0000-0001-7760-2091КучерявыйЮ. А.KucheryavyyYu. A.

Кучерявый Юрий Александрович 

121609 Москва, Крылатская ул., 40, стр. 24

Kucheryavyy Yuriy Aleksandrovich

Build 24, 40 Krylatskaya St., Moscow 121609

https://orcid.org/0000-0002-6581-7017ЛивзанМ. А.LivzanM. A.

Ливзан Мария Анатольевна 

644099 Омск, ул. Ленина, 12

Livzan Maria Anatolyevna

12 Lenina St., Omsk 644099

https://orcid.org/0000-0001-6114-564XМаевИ. В.MaevI. V.

Маев Игорь Вениаминович 

127473 Москва, ул. Делегатская, 20, стр. 1 

Maev Igor Veniaminovich

Build. 1, 20 Delegatskaya St., Moscow 127473

https://orcid.org/0000-0001-6816-3058МорозовС. В.MorozovS. V.

Морозов Сергей Владимирович 

109240 Москва, Устьинский проезд, 2 / 14

125993 Москва, ул. Баррикадная, 2 / 1, стр. 1 

Morozov Sergey Vladimirovich

2/14 Ustinsky Pr., Moscow 109240

Build. 1,2/1 Barrikadnaya St., Moscow 125993

https://orcid.org/0000-0002-5156-2842ОсипенкоМ. Ф.OsipenkoM. F.

Осипенко Марина Федоровна 

Новосибирск, 630091 Новосибирск, ул. Красный проспект, 52 

Osipenko Marina Fedorovna

52 Red prospekt St., Novosibirsk 630091

https://orcid.org/0000-0003-2280-3931ПасечниковВ. Д.PasechnikovV. D.

Пасечников Виктор Дмитриевич 

355035 Ставрополь, ул. Комсомольская, 65 А 

Pasechnikov Viktor Dmitrievich

65 A Komsomolskaya St., Stavropol 355035

https://orcid.org/0000-0001-5543-199XСеменовН. Е.SemenovN. E.

Семенов Николай Евгеньевич 

111123 Москва, Новогиреевская ул., 1, корп. 1 

Semenov Nikolay Evgenievich

Build. 1, 1 Novogireevskaya St., Moscow 111123

 

n.semenov@mknc.ruХомерикиС. Г.KhomerikiS. G.

111123 Москва, Новогиреевская ул., 1, корп. 1 

Build. 1, 1 Novogireevskaya St., Moscow 111123

https://orcid.org/0000-0002-9980-2294ЦукановВ. В.TsukanovV. V.

Цуканов Владислав Владимирович 

660022 Красноярск, ул. Партизана Железняка, 3Г 

Tsukanov Vladislav Vladimirovich

3G Partisan Zheleznyak St., Krasnoyarsk 660022

https://orcid.org/0000-0002-6479-9515ЭмбутниексЮ. В.EmbutnieksYu. V.

Эмбутниекс Юлия Викторовна 

111123 Москва, Новогиреевская ул., 1, корп. 1 

Embutnieks Yulia Viktorovna

Build. 1, 1 Novogireevskaya St., Moscow 111123

ФГАОУ ВО «Казанский (Приволжский) федеральный университет»РоссияKazan (Volga Region) Federal UniversityRussian FederationФГБОУ ВО «Дальневосточный государственный медицинский университет» Минздрава РоссииРоссияFar Eastern State Medical University of the Ministry of Health of the Russian FederationRussian FederationФГБОУ ВО «Московский государственный медико-стоматологический университет им. А. И. Евдокимова» Минздрава РоссииРоссияA. I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of RussiaRussian FederationФГБОУ ВО «Северо-Западный государственный медицинский университет им. И. И. Мечникова» Минздрава РоссииРоссияNorth-Western State Medical University named after I.I. MechnikovRussian FederationГБУЗ г. Москвы «Московский клинический научно-практический центр им. А. С. Логинова Департамента здравоохранения г. Москвы»РоссияA. S. Loginov Moscow Clinical Scientific Center, Moscow Healthcare DepartmentRussian FederationФГБУН «ФИЦ питания, биотехнологии и безопасности пищи»РоссияFederal Research Center for Nutrition, Biotechnology and Food SafetyRussian FederationНаучно-исследовательский институт терапии и профилактической медицины филиал ФГБНУ «ФИЦ ИЦиГ СО РАН»РоссияResearch Institute of Internal and Preventive Medicine Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of SciencesRussian FederationНУЗ ЦКБ № 2 им. Н. А. Семашко ОАО «РЖД»РоссияCentral Clinical Hospital No. 2 named after N. A. Semashko of Russian RailwaysRussian FederationФГБОУ ВО «Омский государственный медицинский университет» Минздрава РоссииРоссияOmsk State Medical University, Ministry of Health of RussiaRussian FederationФГБУН «ФИЦ питания, биотехнологии и безопасности пищи» ; ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава РоссииРоссияFederal Research Center for Nutrition, Biotechnology and Food Safety ; Russian Medical Academy of Continuing Professional Education, Ministry of Health of RussiaRussian FederationМедицинский консультативный центр ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава РоссииРоссияMedical Advisory Center of Novosibirsk State Medical University, Ministry of Health of RussiaRussian FederationЧУ «Центр образовательной и клинической гастроэнтерологии гепатологии и панкреатологии»РоссияCenter for Educational and Clinical Gastroenterology, Hepatology and PancreatologyRussian FederationФГБНУ «ФИЦ Красноярский научный центр Сибирского отделения РАН», НИИ медицинских проблем СевераРоссияFederal Research Center “Krasnoyarsk Scientific Center of the Siberian Branch of the Russian Academy of Sciences» Research Institute for Medical Problems of the NorthRussian Federation2025301020251536878Copyright © Абдулхаков С.Р., Алексеенко С.А., Андреев Д.Н., Бакулина Н.В., Бордин Д.С., Израилов Р.Е., Исаков В.А., Курилович С.А., Кучерявый Ю.А., Ливзан М.А., Маев И.В., Морозов С.В., Осипенко М.Ф., Пасечников В.Д., Семенов Н.Е., Хомерики С.Г., Цуканов В.В., Эмбутниекс Ю.В., 20252025Абдулхаков С.Р., Алексеенко С.А., Андреев Д.Н., Бакулина Н.В., Бордин Д.С., Израилов Р.Е., Исаков В.А., Курилович С.А., Кучерявый Ю.А., Ливзан М.А., Маев И.В., Морозов С.В., Осипенко М.Ф., Пасечников В.Д., Семенов Н.Е., Хомерики С.Г., Цуканов В.В., Эмбутниекс Ю.В.Abdulkhakov S.R., Alekseenko S.A., Andreev D.N., Bakulina N.V., Bordin D.S., Izrailov R.E., Isakov V.A., Kurilovich S.A., Kucheryavyy Y.A., Livzan M.A., Maev I.V., Morozov S.V., Osipenko M.F., Pasechnikov V.D., Semenov N.E., Khomeriki S.G., Tsukanov V.V., Embutnieks Y.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.malignanttumors.org/jour/article/view/1497

Российский консенсус по профилактике, диагностике и лечению рака желудка подготовлен по инициативе Московского клинического научного центра им А. С. Логинова ДЗМ по Дельфийской системе. Его целью явилась консолидация мнений отечественных специалистов по наиболее актуальным вопросам профилактики, скрининга, диагностики и лечения рака желудка. Междисциплинарный подход обеспечен участием ведущих гастроэнтерологов, онкологов и хирургов.

The Russian consensus on prevention, diagnostics and treatment of gastric cancer was prepared on the initiative of the Moscow clinical scientific center named after A. S. Loginov on the Delphi method. Its aim was to clarify and consolidate the opinions of specialists on the most relevant issues of prevention, diagnostics and treatment of gastric cancer. An interdisciplinary approach was provided by the participation of leading gastroen­terologists, oncologists and surgeons.

консенсусрак желудкахирургическое лечение рака желудкаинструментальная диагностика рака желудкалекарственное лечение рака желудкаскрининг и профилактика рака желудкаconsensusgastric cancer preventiongastric cancer diagnosisgastric cancer treatmentReferencesPormohammad A., Mohtavinejad N., Gholizadeh P., et al. Global estimate of gastric cancer in Helicobacter pylori-in-fected population: A systematic review and meta-analysis. J Cell Physiol 2019;234(2):1208-1218. https://doi.org/10.1002/jcp.27114Pormohammad A., Mohtavinejad N., Gholizadeh P., et al. Global estimate of gastric cancer in Helicobacter pylori-in-fected population: A systematic review and meta-analysis. J Cell Physiol 2019;234(2):1208-1218. https://doi.org/10.1002/jcp.27114Uemura N., Okamoto S., Yamamoto S., et al. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 2001;345(ll):784-9. https://doi.org/10.1056/NEJMoa001999Uemura N., Okamoto S., Yamamoto S., et al. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 2001;345(ll):784-9. https://doi.org/10.1056/NEJMoa001999Hsu P.I., Lai K.H., Hsu P.N., et al. Helicobacter pylori infection and the risk of gastric malignancy. Am J Gastroenterol 2007;102(4):725-30. https://doi.Org/10.llll/j.1572-0241.2006.01109.xHsu P.I., Lai K.H., Hsu P.N., et al. Helicobacter pylori infection and the risk of gastric malignancy. Am J Gastroenterol 2007;102(4):725-30. https://doi.Org/10.llll/j.1572-0241.2006.01109.xKamangar F., Qiao Y.L., Blaser M.J., et al. Helicobacter pylori and oesophageal and gastric cancers in a prospective study in China. BrJ Cancer 2007;96(l):172—6. https://doi.org/10.1038/sj.bjc.6603517Kamangar F., Qiao Y.L., Blaser M.J., et al. Helicobacter pylori and oesophageal and gastric cancers in a prospective study in China. BrJ Cancer 2007;96(l):172—6. https://doi.org/10.1038/sj.bjc.6603517Matos J.I., de Sousa H.A., Marcos-Pinto R., Dinis-Ribeiro M. Helicobacter pylori CagA and VacA genotypes and gastric phenotype: a meta-analysis. Eur J Gastroenterol Hepatol 2013;25(12):1431—41. https://doi.org/10.1097/MEG.0b013e-328364b53eMatos J.I., de Sousa H.A., Marcos-Pinto R., Dinis-Ribeiro M. Helicobacter pylori CagA and VacA genotypes and gastric phenotype: a meta-analysis. Eur J Gastroenterol Hepatol 2013;25(12):1431—41. https://doi.org/10.1097/MEG.0b013e-328364b53eKpoghomou M.A., Wang J., Wang T., Jin G. Association of Helicobacter pylori babA2 gene and gastric cancer risk: ameta-analysis. BMC Cancer 2020;20(l):465. https://doi.org/10.1186/sl2885-020-06962-7Kpoghomou M.A., Wang J., Wang T., Jin G. Association of Helicobacter pylori babA2 gene and gastric cancer risk: ameta-analysis. BMC Cancer 2020;20(l):465. https://doi.org/10.1186/sl2885-020-06962-7Malfertheiner P., Megraud F., O’Morain C.A., et al. Management of Helicobacter pylori infection-the Maastricht V/ Florence Consensus Report. Gut 2017;66(l):6-30. https://doi.org/10.1136/gutjnl-2016-312288Malfertheiner P., Megraud F., O’Morain C.A., et al. Management of Helicobacter pylori infection-the Maastricht V/ Florence Consensus Report. Gut 2017;66(l):6-30. https://doi.org/10.1136/gutjnl-2016-312288Sugano K., Tack J., Kuipers E.J., et al. Kyoto global consensus report on Helicobacter pylori gastritis. Gut 2015;64(9):1353— 67. https://doi.org/10.1136/gutjnl-2015-309252Sugano K., Tack J., Kuipers E.J., et al. Kyoto global consensus report on Helicobacter pylori gastritis. Gut 2015;64(9):1353— 67. https://doi.org/10.1136/gutjnl-2015-309252Pimentel-Nunes Р., Libanio D., Marcos-Pinto R., et al. Management of epithelial precancerous conditions and lesions in the stomach (MAPS II): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG), European Society of Pathology (ESP), and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideline update 2019. Endoscopy 2019;51(4):365-388. https://doi.org/10.1055/a-0859-1883Pimentel-Nunes Р., Libanio D., Marcos-Pinto R., et al. Management of epithelial precancerous conditions and lesions in the stomach (MAPS II): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG), European Society of Pathology (ESP), and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideline update 2019. Endoscopy 2019;51(4):365-388. https://doi.org/10.1055/a-0859-1883Ивашкин B.T., Маев И.В., Лапина Т.Л. и соавт. Клинические рекомендации Российской гастроэнтерологической ассоциации по диагностике и лечению инфекции Helicobacter pylori у взрослых. Рос журн гастроэнтерол гепатол колопроктол 2018;28(1):55-70. https://doi.org/10.22416/1382-4376-2018-28-l-55-70.Ivashkin V.T., Mayev I.V., Lapina T.L., et al. Diagnostics and treatment of Helicobacter pylori infection in adults: Clinical guidelines of the Russian gastroenterological association. Ross z gastroenterol gepatol koloproktol 2018;28(l):55-70 (In Russ.), https://doi.org/10.22416/1382-4376-2018-28-l-55-70Ивашкин B.T., Маев H.B., Каприн А.Д. и соавт. Раннее выявление онкологических заболеваний органов пищеварения (методическое руководство Российской гастроэнтерологической ассоциации и Ассоциации онкологов России для врачей первичного звена здравоохранения). Российский журнал гастроэнтерологии, гепатологии, колопроктологии 2019;29(5):53—74. https://doi.org/10.22416/1382-4376-2019-29-5-53-74.Ivashkin V.T., Mayev I.V., Kaprin A.D., et al. Early Detection of Oncological Diseases of the Digestive System (Guidelines of the Russian Gastroenterological Association and the Russian Association of Oncologists for Primary Care Physicians). Russian Journal of Gastroenterology, Hepatology, Coloproctology 2019;29(5):53-74 (In Russ.), https://doi.org/10.22416/1382-4376-2019-29-5-53-74Chiang T.H., Chang W.J., Chen S.L., et al. Mass eradication of Helicobacter pylori to reduce gastric cancer incidence and mortality: a long-term cohort study on Matsu Islands. Gut 2021;70(2):243-250. https://doi.org/10.1136/gutjnl-2020-322200Chiang T.H., Chang W.J., Chen S.L., et al. Mass eradication of Helicobacter pylori to reduce gastric cancer incidence and mortality: a long-term cohort study on Matsu Islands. Gut 2021;70(2):243-250. https://doi.org/10.1136/gutjnl-2020-322200Liou J.M., Malfertheiner P., Lee Y.C., et al; Asian Pacific Alliance on Helicobacter and Microbiota (АРАНАМ). Screening and eradication of Helicobacter pylori for gastric cancer prevention: the Taipei global consensus. Gut 2020;69(12):2093-2112. https://doi.org/10.1136/gutjnl-2020-322368Liou J.M., Malfertheiner P., Lee Y.C., et al; Asian Pacific Alliance on Helicobacter and Microbiota (АРАНАМ). Screening and eradication of Helicobacter pylori for gastric cancer prevention: the Taipei global consensus. Gut 2020;69(12):2093-2112. https://doi.org/10.1136/gutjnl-2020-322368Pan K.F., Zhang L., Gerhard M., et al. A large randomised controlled intervention trial to prevent gastric cancer by eradication of Helicobacter pylori in Linqu County, China: baseline results and factors affecting the eradication. Gut 2016;65(1):9-18. https://doi.org/10.1136/gutjnl-2015-309197Pan K.F., Zhang L., Gerhard M., et al. A large randomised controlled intervention trial to prevent gastric cancer by eradication of Helicobacter pylori in Linqu County, China: baseline results and factors affecting the eradication. Gut 2016;65(1):9-18. https://doi.org/10.1136/gutjnl-2015-309197Pimentel-Nunes P., Libanio D., Marcos-Pinto R., et al. Management of epithelial precancerous conditions and lesions in the stomach (MAPS II): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG), European Society of Pathology (ESP), and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideline update 2019. Endoscopy 2019;51(4):365-388. https://doi.org/10.1055/a-0859-1883Pimentel-Nunes P., Libanio D., Marcos-Pinto R., et al. Management of epithelial precancerous conditions and lesions in the stomach (MAPS II): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG), European Society of Pathology (ESP), and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideline update 2019. Endoscopy 2019;51(4):365-388. https://doi.org/10.1055/a-0859-1883Sugano K. Effect of Helicobacter pylori eradication on the incidence of gastric cancer: a systematic review and meta-analysis. Gastric Cancer 2019;22(3):435-445. https://doi.org/10.1007/sl0120-018-0876-0Sugano K. Effect of Helicobacter pylori eradication on the incidence of gastric cancer: a systematic review and meta-analysis. Gastric Cancer 2019;22(3):435-445. https://doi.org/10.1007/sl0120-018-0876-0Bang C.S., Baik G.H., Shin I.S., et al. Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer. J Korean Med Sci 2015;30(6):749-56. https://doi.org/10.3346/jkms.2015.30.6.749Bang C.S., Baik G.H., Shin I.S., et al. Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer. J Korean Med Sci 2015;30(6):749-56. https://doi.org/10.3346/jkms.2015.30.6.749Jung D.H., Kim J.H., Chung H.S., et al. Helicobacter pylori Eradication on the Prevention of Metachronous Lesions after Endoscopic Resection of Gastric Neoplasm: A Meta-Analysis. PLoS One 2015;10(4):e0124725. https://doi.org/10.1371/journal.pone.0124725Jung D.H., Kim J.H., Chung H.S., et al. Helicobacter pylori Eradication on the Prevention of Metachronous Lesions after Endoscopic Resection of Gastric Neoplasm: A Meta-Analysis. PLoS One 2015;10(4):e0124725. https://doi.org/10.1371/journal.pone.0124725Yoon S.B., Park J.M., Lim С. H, et al. Effect of Helicobacter pylori eradication on metachronous gastric cancer after endoscopic resection of gastric tumors: a meta-analysis. Helicobacter 2014;19(4):243—8. https://doi.org/10.llll/hel.12146Yoon S.B., Park J.M., Lim С. H, et al. Effect of Helicobacter pylori eradication on metachronous gastric cancer after endoscopic resection of gastric tumors: a meta-analysis. Helicobacter 2014;19(4):243—8. https://doi.org/10.llll/hel.12146Lee Y.C., Chiang T.H., Chou C.K., et al. Association Between Helicobacter pylori Eradication and Gastric Cancer Incidence: A Systematic Review and Meta-analysis. Gastroenterology 2016;150(5):1113-1124.e5. https://doi.org/10.1053/j.gastro.2016.01.028Lee Y.C., Chiang T.H., Chou C.K., et al. Association Between Helicobacter pylori Eradication and Gastric Cancer Incidence: A Systematic Review and Meta-analysis. Gastroenterology 2016;150(5):1113-1124.e5. https://doi.org/10.1053/j.gastro.2016.01.028Xiao S., Li S., Zhou L., et al. Helicobacter pylori status and risks of metachronous recurrence after endoscopic resection of early gastric cancer: a systematic review and meta-analysis. J Gastroenterol 2019;54(3):226—237. https://doi.org/10.1007/s00535-018-1513-8Xiao S., Li S., Zhou L., et al. Helicobacter pylori status and risks of metachronous recurrence after endoscopic resection of early gastric cancer: a systematic review and meta-analysis. J Gastroenterol 2019;54(3):226—237. https://doi.org/10.1007/s00535-018-1513-8Jung D.H., Lee Y.C., Kim J.H., et al. Postoperative Helicobacter pylori Infection as a Prognostic Factor for Gastric Cancer Patients after Curative Resection. Gut Liver 2017;ll(5):635—641. https://doi.org/10.5009/gnll6397Jung D.H., Lee Y.C., Kim J.H., et al. Postoperative Helicobacter pylori Infection as a Prognostic Factor for Gastric Cancer Patients after Curative Resection. Gut Liver 2017;ll(5):635—641. https://doi.org/10.5009/gnll6397Kim Y.I., Cho S.J., Lee J.Y., et al. Effect of Helicobacter pylori Eradication on Long-Term Survival after Distal Gastrectomy for Gastric Cancer. Cancer Res Treat 2016;48(3):1020-9. https://doi.org/10.4143/crt.2015.264Kim Y.I., Cho S.J., Lee J.Y., et al. Effect of Helicobacter pylori Eradication on Long-Term Survival after Distal Gastrectomy for Gastric Cancer. Cancer Res Treat 2016;48(3):1020-9. https://doi.org/10.4143/crt.2015.264Yoon K., Kim N., Kim J., et al. Dynamic Changes in Helicobacter pylori Status Following Gastric Cancer Surgery. Gut Liver 2017;ll(2):209-215. https://doi.org/10.5009/gnll6224Yoon K., Kim N., Kim J., et al. Dynamic Changes in Helicobacter pylori Status Following Gastric Cancer Surgery. Gut Liver 2017;ll(2):209-215. https://doi.org/10.5009/gnll6224Miyashita T., Miwa K., Inokuchi M., et al. Spontaneous clearance of Helicobacter pylori after pylorus-preserving gastrectomy for gastric cancer. Oncol Rep 2013;30(l):299-303. https://doi.org/10.3892/or.2013.2472Miyashita T., Miwa K., Inokuchi M., et al. Spontaneous clearance of Helicobacter pylori after pylorus-preserving gastrectomy for gastric cancer. Oncol Rep 2013;30(l):299-303. https://doi.org/10.3892/or.2013.2472Zullo A., Hassan C., Romiti A., et al. Follow-up of intestinal metaplasia in the stomach: When, how and why. World J Gastrointest Oncol 2012;4(3):30-6. https://doi.org/10.4251/wjgo.v4.i3.30Zullo A., Hassan C., Romiti A., et al. Follow-up of intestinal metaplasia in the stomach: When, how and why. World J Gastrointest Oncol 2012;4(3):30-6. https://doi.org/10.4251/wjgo.v4.i3.30Park Y.H., Kim N. Review of atrophic gastritis and intestinal metaplasia as a premalignant lesion of gastric cancer. J Cancer Prev 2015;20(l):25-40. https://doi.Org/10.15430/JCP.2015.20.l.25Park Y.H., Kim N. Review of atrophic gastritis and intestinal metaplasia as a premalignant lesion of gastric cancer. J Cancer Prev 2015;20(l):25-40. https://doi.Org/10.15430/JCP.2015.20.l.25Gonzalez C.A., Sanz-Anquela J.M., Companioni O., et al. Incomplete type of intestinal metaplasia has the highest risk to progress to gastric cancer: results of the Spanish follow-up multicenter study. J Gastroenterol Hepatol 2016;31(5):953-8. https://doi.org/10.llll/jgh.13249Gonzalez C.A., Sanz-Anquela J.M., Companioni O., et al. Incomplete type of intestinal metaplasia has the highest risk to progress to gastric cancer: results of the Spanish follow-up multicenter study. J Gastroenterol Hepatol 2016;31(5):953-8. https://doi.org/10.llll/jgh.13249Banks M., Graham D., Jansen M., et al. British Society of Gastroenterology guidelines on the diagnosis and management of patients at risk of gastric adenocarcinoma. Gut 2019;68(9):1545-1575. https://doi.org/10.1136/gutjnl-2018-318126Banks M., Graham D., Jansen M., et al. British Society of Gastroenterology guidelines on the diagnosis and management of patients at risk of gastric adenocarcinoma. Gut 2019;68(9):1545-1575. https://doi.org/10.1136/gutjnl-2018-318126Dinis-Ribeiro M., Lopes C., da Costa-Pereira A., et al. A follow up model for patients with atrophic chronic gastritis and intestinal metaplasia. J Clin Pathol 2004;57(2):177-82. https://doi.org/10.1136/jcp.2003.11270Dinis-Ribeiro M., Lopes C., da Costa-Pereira A., et al. A follow up model for patients with atrophic chronic gastritis and intestinal metaplasia. J Clin Pathol 2004;57(2):177-82. https://doi.org/10.1136/jcp.2003.11270Mera R.M., Bravo L.E., Camargo M.C., et al. Dynamics of Helicobacter pylori infection as a determinant of progression of gastric precancerous lesions: 16-year follow-up of an eradication trial. Gut 2018;67(7):1239-1246. https://doi.org/10.1136/gutjnl-2016-311685Mera R.M., Bravo L.E., Camargo M.C., et al. Dynamics of Helicobacter pylori infection as a determinant of progression of gastric precancerous lesions: 16-year follow-up of an eradication trial. Gut 2018;67(7):1239-1246. https://doi.org/10.1136/gutjnl-2016-311685Pimentel-Nunes P., Libanio D., Marcos-Pinto R., et al. Management of epithelial precancerous conditions and lesions in the stomach (MAPS II): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG), European Society of Pathology (ESP), and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideline update 2019. Endoscopy 2019;51(4):365-388. https://doi.org/10.1055/a-0859-1883Pimentel-Nunes P., Libanio D., Marcos-Pinto R., et al. Management of epithelial precancerous conditions and lesions in the stomach (MAPS II): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG), European Society of Pathology (ESP), and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideline update 2019. Endoscopy 2019;51(4):365-388. https://doi.org/10.1055/a-0859-1883Yue H., Shan L., Bin L. The significance of OLGA and OLGIM staging systems in the risk assessment of gastric cancer: a systematic review and meta-analysis. Gastric Cancer 2018;21(4):579-587. https://doi.org/10.1007/sl0120-018-0812-3Yue H., Shan L., Bin L. The significance of OLGA and OLGIM staging systems in the risk assessment of gastric cancer: a systematic review and meta-analysis. Gastric Cancer 2018;21(4):579-587. https://doi.org/10.1007/sl0120-018-0812-3Shichijo S., Hirata Y., Niikura R., et al. Histologic intestinal metaplasia and endoscopic atrophy are predictors of gastric cancer development after Helicobacter pylori eradication. Gastrointest Endosc 2016;84(4):618-24. https://doi.org/10.1016/j.gie.2016.03.791Shichijo S., Hirata Y., Niikura R., et al. Histologic intestinal metaplasia and endoscopic atrophy are predictors of gastric cancer development after Helicobacter pylori eradication. Gastrointest Endosc 2016;84(4):618-24. https://doi.org/10.1016/j.gie.2016.03.791Take S., Mizuno M., Ishiki K., et al. Risk of gastric cancer in the second decade of follow-up after Helicobacter pylori eradication. J Gastroenterol 2020;55(3):281-288. https://doi.org/10.1007/s00535-019-01639-wTake S., Mizuno M., Ishiki K., et al. Risk of gastric cancer in the second decade of follow-up after Helicobacter pylori eradication. J Gastroenterol 2020;55(3):281-288. https://doi.org/10.1007/s00535-019-01639-wHamashima C. Systematic Review Group and Guideline Development Group for Gastric Cancer Screening Guidelines. Update version of the Japanese Guidelines for Gastric Cancer Screening. Jpn J Clin Oncol 2018;48(7):673-683. https://doi.org/10.1093/jjco/hyy077Hamashima C. Systematic Review Group and Guideline Development Group for Gastric Cancer Screening Guidelines. Update version of the Japanese Guidelines for Gastric Cancer Screening. Jpn J Clin Oncol 2018;48(7):673-683. https://doi.org/10.1093/jjco/hyy077Kim G.H., Liang P.S., Bang S.J., Hwang J.H. Screening and surveillance for gastric cancer in the United States: Is it needed? Gastrointest Endosc 2016;84(l):18-28. https://doi.Org/10.1016/j.gie.2016.02.028Kim G.H., Liang P.S., Bang S.J., Hwang J.H. Screening and surveillance for gastric cancer in the United States: Is it needed? Gastrointest Endosc 2016;84(l):18-28. https://doi.Org/10.1016/j.gie.2016.02.028Yao K., Uedo N., Kamada T., et al. Guidelines for endoscopic diagnosis of early gastric cancer. Dig Endosc 2020;32(5):663-698. https://doi.org/10.llll/den.13684Yao K., Uedo N., Kamada T., et al. Guidelines for endoscopic diagnosis of early gastric cancer. Dig Endosc 2020;32(5):663-698. https://doi.org/10.llll/den.13684Eusebi L.H., Telese A., Marasco G., et al. Gastric cancer prevention strategies: A global perspective. J Gastroenterol Hepatol 2020;35(9):1495—1502. https://doi.org/10.llll/jgh.15037Eusebi L.H., Telese A., Marasco G., et al. Gastric cancer prevention strategies: A global perspective. J Gastroenterol Hepatol 2020;35(9):1495—1502. https://doi.org/10.llll/jgh.15037Sugano K., Tack J., Kuipers E.J., et al; faculty members of Kyoto Global Consensus Conference. Kyoto global consensus report on Helicobacter pylori gastritis. Gut 2015;64(9):1353—67. https://doi.org/10.1136/gutjnl-2015-309252Sugano K., Tack J., Kuipers E.J., et al; faculty members of Kyoto Global Consensus Conference. Kyoto global consensus report on Helicobacter pylori gastritis. Gut 2015;64(9):1353—67. https://doi.org/10.1136/gutjnl-2015-309252Malfertheiner P., Megraud F., O’Morain C.A., et al; European Helicobacter and Microbiota Study Group and Consensus panel. Management of Helicobacter pylori infection-the Maastricht V/Florence Consensus Report. Gut 2017;66(l):6-30. https://doi.org/10.1136/gutjnl-2016-312288Malfertheiner P., Megraud F., O’Morain C.A., et al; European Helicobacter and Microbiota Study Group and Consensus panel. Management of Helicobacter pylori infection-the Maastricht V/Florence Consensus Report. Gut 2017;66(l):6-30. https://doi.org/10.1136/gutjnl-2016-312288Pimentel-Nunes P., Libanio D., Marcos-Pinto R., et al. Management of epithelial precancerous conditions and lesions in the stomach (MAPS II): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG), European Society of Pathology (ESP), and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideline update 2019. Endoscopy 2019;51(4):365-388. https://doi.org/10.1055/a-0859-1883Pimentel-Nunes P., Libanio D., Marcos-Pinto R., et al. Management of epithelial precancerous conditions and lesions in the stomach (MAPS II): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG), European Society of Pathology (ESP), and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideline update 2019. Endoscopy 2019;51(4):365-388. https://doi.org/10.1055/a-0859-1883Yamaguchi Y., Nagata Y., Hiratsuka R., et al. Gastric Cancer Screening by Combined Assay for Serum Anti-Helicobacter pylori IgG Antibody and Serum Pepsinogen Levels—The ABC Method. Digestion 2016;93(l):13-8. https://doi.org/10.1159/000441742Yamaguchi Y., Nagata Y., Hiratsuka R., et al. Gastric Cancer Screening by Combined Assay for Serum Anti-Helicobacter pylori IgG Antibody and Serum Pepsinogen Levels—The ABC Method. Digestion 2016;93(l):13-8. https://doi.org/10.1159/000441742Huang Y.K., Yu J.C., Kang W.M., et al. Significance of Serum Pepsinogens as a Biomarker for Gastric Cancer and Atrophic Gastritis Screening: A Systematic Review and Meta-Analysis. PLoS One 2015;10(ll):e0142080. https://doi.org/10.1371/journal.pone.0142080Huang Y.K., Yu J.C., Kang W.M., et al. Significance of Serum Pepsinogens as a Biomarker for Gastric Cancer and Atrophic Gastritis Screening: A Systematic Review and Meta-Analysis. PLoS One 2015;10(ll):e0142080. https://doi.org/10.1371/journal.pone.0142080Sheu B.S., Wu M.S., Chiu C.T., et al. Consensus on the clinical management, screening-to-treat, and surveillance of Helicobacter pylori infection to improve gastric cancer control on a nationwide scale. Helicobacter 2017;22(3):el2368. https://doi.org/10.llll/hel.12368Sheu B.S., Wu M.S., Chiu C.T., et al. Consensus on the clinical management, screening-to-treat, and surveillance of Helicobacter pylori infection to improve gastric cancer control on a nationwide scale. Helicobacter 2017;22(3):el2368. https://doi.org/10.llll/hel.12368Liou J.M., Malfertheiner P., Lee Y.C., et al; Asian Pacific Alliance on Helicobacter and Microbiota (АРАНАМ). Screening and eradication of Helicobacter pylori for gastric cancer prevention: the Taipei global consensus. Gut 2020;69(12):2093-2112. https://doi.org/10.1136/gutjnl-2020-322368Liou J.M., Malfertheiner P., Lee Y.C., et al; Asian Pacific Alliance on Helicobacter and Microbiota (АРАНАМ). Screening and eradication of Helicobacter pylori for gastric cancer prevention: the Taipei global consensus. Gut 2020;69(12):2093-2112. https://doi.org/10.1136/gutjnl-2020-322368Zhang X., Li M., Chen S., et al. Endoscopic Screening in Asian Countries Is Associated With Reduced Gastric Cancer Mortality: A Meta-analysis and Systematic Review. Gastroenterology 2018;155(2):347-354.e9. https://doi.Org/10.1053/j.gastro.2018.04.026Zhang X., Li M., Chen S., et al. Endoscopic Screening in Asian Countries Is Associated With Reduced Gastric Cancer Mortality: A Meta-analysis and Systematic Review. Gastroenterology 2018;155(2):347-354.e9. https://doi.Org/10.1053/j.gastro.2018.04.026Liu М., Не Z., Guo С., et al. Effectiveness of Intensive Endoscopic Screening for Esophageal Cancer in China: A Community-Based Study. AmJ Epidemiol 2019;188(4):776-784. https://doi.org/10.1093/aje/kwy291Liu М., Не Z., Guo С., et al. Effectiveness of Intensive Endoscopic Screening for Esophageal Cancer in China: A Community-Based Study. AmJ Epidemiol 2019;188(4):776-784. https://doi.org/10.1093/aje/kwy291Wei W.Q., Chen Z.F., He Y.T., et al. Long-Term Follow-Up of a Community Assignment, One-Time Endoscopic Screening Study of Esophageal Cancer in China. J Clin Oncol 2015;33(17):1951-7. https://doi.org/10.1200/JCO.2014.58.0423Wei W.Q., Chen Z.F., He Y.T., et al. Long-Term Follow-Up of a Community Assignment, One-Time Endoscopic Screening Study of Esophageal Cancer in China. J Clin Oncol 2015;33(17):1951-7. https://doi.org/10.1200/JCO.2014.58.0423Chen R., Liu Y., Song G., et al. Effectiveness of one-time endoscopic screening programme in prevention of upper gastrointestinal cancer in China: a multicentre population-based cohort study. Gut 2021;70(2):251-260. https://doi.org/10.1136/gutjnl-2019-320200Chen R., Liu Y., Song G., et al. Effectiveness of one-time endoscopic screening programme in prevention of upper gastrointestinal cancer in China: a multicentre population-based cohort study. Gut 2021;70(2):251-260. https://doi.org/10.1136/gutjnl-2019-320200Kim H., Hwang Y., Sung H., et al. Effectiveness of Gastric Cancer Screening on Gastric Cancer Incidence and Mortality in a Community-Based Prospective Cohort. Cancer Res Treat 2018;50(2):582-589. https://doi.org/10.4143/crt.2017.048Kim H., Hwang Y., Sung H., et al. Effectiveness of Gastric Cancer Screening on Gastric Cancer Incidence and Mortality in a Community-Based Prospective Cohort. Cancer Res Treat 2018;50(2):582-589. https://doi.org/10.4143/crt.2017.048Клинические рекомендации. Рак желудка, 2020. Доступно по: https://oncology-association.ru/wp-content/uploads/2020/09/rak_zheludka.pdf.Clinical Guidelines. Stomach cancer, 2020. Available at: https://oncology-association.ru/wp-content/uploads/2020/09/rak_zheludka.pdf (In Russ.)Wu C., Han R., Yang S., et al. A case-control study of microRNA polymorphisms in gastric cancer screening by SNP chip combined with time of flight mass spectrometry. Biomark Med 2020;14(16):1563-1572. https://doi.org/10.2217/bmm-2020-0003Wu C., Han R., Yang S., et al. A case-control study of microRNA polymorphisms in gastric cancer screening by SNP chip combined with time of flight mass spectrometry. Biomark Med 2020;14(16):1563-1572. https://doi.org/10.2217/bmm-2020-0003Huang H.L., Leung C.Y., Saito E., et al. Effect and cost-effectiveness of national gastric cancer screening in Japan: amicrosimulation modeling study. BMC Med 2020;18(1):257. https://doi.org/10.1186/sl2916-020-01729-0Huang H.L., Leung C.Y., Saito E., et al. Effect and cost-effectiveness of national gastric cancer screening in Japan: amicrosimulation modeling study. BMC Med 2020;18(1):257. https://doi.org/10.1186/sl2916-020-01729-0Ge X., Zhang X., Ma Y., et al. Diagnostic value of macrophage inhibitory cytokine 1 as a novel prognostic biomarkers for early gastric cancer screening. J Clin Lab Anal 2021;35(l):e23568. https://doi.org/10.1002/jcla.23568Ge X., Zhang X., Ma Y., et al. Diagnostic value of macrophage inhibitory cytokine 1 as a novel prognostic biomarkers for early gastric cancer screening. J Clin Lab Anal 2021;35(l):e23568. https://doi.org/10.1002/jcla.23568Kapoor R., So J.B.Y., Zhu F., et al. Evaluating the Use of microRNA Blood Tests for Gastric Cancer Screening in a Stratified Population-Level Screening Program: An Early Model-Based Cost-Effectiveness Analysis. Value Health 2020;23(9):1171-1179. https://doi.Org/10.1016/j.jval.2020.04.1829Kapoor R., So J.B.Y., Zhu F., et al. Evaluating the Use of microRNA Blood Tests for Gastric Cancer Screening in a Stratified Population-Level Screening Program: An Early Model-Based Cost-Effectiveness Analysis. Value Health 2020;23(9):1171-1179. https://doi.Org/10.1016/j.jval.2020.04.1829Shah S.C., Canakis A., Peek R.M. Jr, Saumoy M. Endoscopy for Gastric Cancer Screening Is Cost Effective for Asian Americans in the United States. Clin Gastroenterol Hepatol 2020;18(13):3026-3039. https://doi.Org/10.1016/j.cgh.2020.07.031Shah S.C., Canakis A., Peek R.M. Jr, Saumoy M. Endoscopy for Gastric Cancer Screening Is Cost Effective for Asian Americans in the United States. Clin Gastroenterol Hepatol 2020;18(13):3026-3039. https://doi.Org/10.1016/j.cgh.2020.07.031Canakis A., Pani E., Saumoy M., Shah S.C. Decision model analyses of upper endoscopy for gastric cancer screening and preneoplasia surveillance: a systematic review. Therap Adv Gastroenterol 2020;13:1756284820941662. https://doi.org/10.1177/1756284820941662Canakis A., Pani E., Saumoy M., Shah S.C. Decision model analyses of upper endoscopy for gastric cancer screening and preneoplasia surveillance: a systematic review. Therap Adv Gastroenterol 2020;13:1756284820941662. https://doi.org/10.1177/1756284820941662Kim D.H., Shin N., Kim G.H., et al. Mucin expression in gastric cancer: reappraisal of its clinicopathologic and prognostic significance. Arch Pathol Lab Med 2013;137(8):1047—53. https://doi.org/10.5858/arpa.2012-0193-OAKim D.H., Shin N., Kim G.H., et al. Mucin expression in gastric cancer: reappraisal of its clinicopathologic and prognostic significance. Arch Pathol Lab Med 2013;137(8):1047—53. https://doi.org/10.5858/arpa.2012-0193-OAMartin F.C., Chenevix-Trench G., Yeomans N.D. Systematic review with meta-analysis: fundic gland polyps and proton pump inhibitors. Aliment Pharmacol Ther 2016;44(9):915-925. https://doi.org/10.llll/apt.13800Martin F.C., Chenevix-Trench G., Yeomans N.D. Systematic review with meta-analysis: fundic gland polyps and proton pump inhibitors. Aliment Pharmacol Ther 2016;44(9):915-925. https://doi.org/10.llll/apt.13800Velazquez-Dohorn M., Lopez-Durand C.F., Candanedo-Gonzalez F., et al. Case-control analysis of fundic gland polyps and proton-pump inhibitors. A pathologist’s perspective. Rev Gastroenterol Mex (Engl Ed) 2020;85(l):42-47. https://doi.org/10.1016/j.rgmx.2019.02.007Velazquez-Dohorn M., Lopez-Durand C.F., Candanedo-Gonzalez F., et al. Case-control analysis of fundic gland polyps and proton-pump inhibitors. A pathologist’s perspective. Rev Gastroenterol Mex (Engl Ed) 2020;85(l):42-47. https://doi.org/10.1016/j.rgmx.2019.02.007Yao T., Kajiwara M., Kuroiwa S., et al. Malignant transformation of gastric hyperplastic polyps: alteration of phenotypes, proliferative activity, andp53 expression. Hum Pathol 2002;33(10):1016-22. https://doi.org/10.1053/hupa.2002.126874Yao T., Kajiwara M., Kuroiwa S., et al. Malignant transformation of gastric hyperplastic polyps: alteration of phenotypes, proliferative activity, andp53 expression. Hum Pathol 2002;33(10):1016-22. https://doi.org/10.1053/hupa.2002.126874Straub S.F., Drage M.G., Gonzalez R.S. Comparison of dysplastic fundic gland polyps in patients with and without familial adenomatous polyposis. Histopathology 2018;72(7):1172—1179. https://doi.org/10.llll/his.13485Straub S.F., Drage M.G., Gonzalez R.S. Comparison of dysplastic fundic gland polyps in patients with and without familial adenomatous polyposis. Histopathology 2018;72(7):1172—1179. https://doi.org/10.llll/his.13485Chen Z.M., Scudiere J.R., Abraham S.C., Montgomery E. Pyloric gland adenoma: an entity distinct from gastric foveolar type adenoma. AmJ Surg Pathol 2009;33(2):186-93. https://doi.org/10.1097/PAS.0b013e31817d7ff4Chen Z.M., Scudiere J.R., Abraham S.C., Montgomery E. Pyloric gland adenoma: an entity distinct from gastric foveolar type adenoma. AmJ Surg Pathol 2009;33(2):186-93. https://doi.org/10.1097/PAS.0b013e31817d7ff4Park D.Y., Srivastava A., Kim G.H., et al. Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia. Am J Surg Pathol 2008;32(4):524-33. https://doi.org/10.1097/PAS.0b013e31815b890ePark D.Y., Srivastava A., Kim G.H., et al. Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia. Am J Surg Pathol 2008;32(4):524-33. https://doi.org/10.1097/PAS.0b013e31815b890eUeyama H., Matsumoto K., Nagahara A., et al. Gastric adenocarcinoma of the fundic gland type (chief cell predominant type). Endoscopy 2014;46(2):153-7. https://doi.org/10.1055/s-0033-1359042Ueyama H., Matsumoto K., Nagahara A., et al. Gastric adenocarcinoma of the fundic gland type (chief cell predominant type). Endoscopy 2014;46(2):153-7. https://doi.org/10.1055/s-0033-1359042Choi W.T., Brown I., Ushiku T., et al. Gastric pyloric gland adenoma: a multicentre clinicopathological study of 67 cases. Histopathology 2018;72(6):1007—1014. https://doi.org/10.llll/his.13460Choi W.T., Brown I., Ushiku T., et al. Gastric pyloric gland adenoma: a multicentre clinicopathological study of 67 cases. Histopathology 2018;72(6):1007—1014. https://doi.org/10.llll/his.13460WHO Classification of Tumours Lyon, France: International Agency for Research on Cancer (2020) 5th. Available from: https://tumourclassification.iarc.who.intWHO Classification of Tumours Lyon, France: International Agency for Research on Cancer (2020) 5th. Available from: https://tumourclassification.iarc.who.intKushima R., Kim K.M. Interobserver Variation in the Diagnosis of Gastric Epithelial Dysplasia and Carcinoma between Two Pathologists in Japan and Korea. J Gastric Cancer 2011;ll(3):141-5. https://doi.Org/10.5230/jgc.2011.ll.3.141Kushima R., Kim K.M. Interobserver Variation in the Diagnosis of Gastric Epithelial Dysplasia and Carcinoma between Two Pathologists in Japan and Korea. J Gastric Cancer 2011;ll(3):141-5. https://doi.Org/10.5230/jgc.2011.ll.3.141Rugge M., Cassaro M., Di Mario F.,et al; Interdisciplinary Group on Gastric Epithelial Dysplasia (IGGED). The long term outcome of gastric non-invasive neoplasia. Gut 2003;52(8):llll-6. https://doi.Org/10.1136/gut.52.8.llllRugge M., Cassaro M., Di Mario F.,et al; Interdisciplinary Group on Gastric Epithelial Dysplasia (IGGED). The long term outcome of gastric non-invasive neoplasia. Gut 2003;52(8):llll-6. https://doi.Org/10.1136/gut.52.8.llllBray F., Laversanne M., Sung H., et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA CancerJ Clin 2024;74:229-263. https://doi.org/10.3322/caac.21834Bray F., Laversanne M., Sung H., et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA CancerJ Clin 2024;74:229-263. https://doi.org/10.3322/caac.21834Sung Н., Ferlay J., Siegel R.L., et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA CancerJ Clin 2021;71:209-249. https://doi.org/10.3322/caac.21660Sung Н., Ferlay J., Siegel R.L., et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA CancerJ Clin 2021;71:209-249. https://doi.org/10.3322/caac.21660Conti C.B., Agnesi S., Scaravaglio M., et al. Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment. IntJ Environ Res Public Health 2023;20(3):2149. https://doi.org/10.3390/ijerph20032149.Conti C.B., Agnesi S., Scaravaglio M., et al. Early Gastric Cancer: Update on Prevention, Diagnosis and Treatment. IntJ Environ Res Public Health 2023;20(3):2149. https://doi.org/10.3390/ijerph20032149.

The authors declare that there are no conflicts of interest present.