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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">tumors</journal-id><journal-title-group><journal-title xml:lang="ru">Malignant tumours</journal-title><trans-title-group xml:lang="en"><trans-title>Malignant tumours</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2224-5057</issn><issn pub-type="epub">2587-6813</issn><publisher><publisher-name>Rosoncoweb</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18027/2224-5057-2024-012</article-id><article-id custom-type="elpub" pub-id-type="custom">tumors-1410</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И АНАЛИТИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND ANALYSIS</subject></subj-group></article-categories><title-group><article-title>Ангиосаркома молочной железы (обзор литературы и описание двух клинических наблюдений)</article-title><trans-title-group xml:lang="en"><trans-title>Angiosarcoma of the breast (literature review and description of two clinical observations)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4447-9458</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлова</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlova</surname><given-names>R. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Орлова Рашида Вахидовна</p><p>199034 Санкт-Петербург, Университетская наб., 7-94 198255 Санкт-Петербург, пр-кт Ветеранов, 56</p></bio><bio xml:lang="en"><p>Orlova Rashida Vakhidovna</p><p>7-9 universitetskaya Naberezhnaya, Saint Petersburg 199034; 56 Veteranov Prospekt, Saint Petersburg 198255</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7111-1507</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андросова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Androsova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Андросова Александра Валерьевна</p><p>198255 Санкт-Петербург, пр-кт Ветеранов, 56</p></bio><bio xml:lang="en"><p>Androsova Aleksandra Valerevna</p><p>56 Veteranov Prospekt, Saint Petersburg 198255</p></bio><email xlink:type="simple">alexa.androsova.1711@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2105-2251</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Топузов</surname><given-names>Э. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Topuzov</surname><given-names>E. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Топузов Эльдар Эскендерович</p><p>198255 Санкт-Петербург, пр-кт Ветеранов, 56; 191015 Санкт-Петербург, ул. Кирочная, 41</p></bio><bio xml:lang="en"><p>Topuzov Eldar Eskenderovich</p><p>56 Veteranov Prospekt, Saint Petersburg 198255; 41 Kirochnaya St., Saint Petersburg 191015</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0402-6067</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беляк</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Belyak</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Беляк Наталья Петровна</p><p>199034 Санкт-Петербург, Университетская наб., 7-94 198255 Санкт-Петербург, пр-кт Ветеранов, 56</p></bio><bio xml:lang="en"><p>Belyak Natalya Petrovna</p><p>7-9 Universitetskaya Naberezhnaya, Saint Petersburg 199034; 56 Veteranov Prospekt, Saint Petersburg 198255</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2221-4088</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кутукова</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kutukova</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кутукова Светлана Игоревна</p><p>198255 Санкт-Петербург, пр-кт Ветеранов, 56;197022 Санкт-Петербург, ул. Льва Толстого, 6-8</p></bio><bio xml:lang="en"><p>Kutukova Svetlana Igorevna</p><p>56 Veteranov Prospekt, Saint Petersburg 198255; 197022 Санкт-Петербург, ул. Аъеа Толстого, 6—8</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авраменко</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Avramenko</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>198255 Санкт-Петербург, пр-кт Ветеранов, 56</p></bio><bio xml:lang="en"><p>56 Veteranov Prospekt, Saint Petersburg 198255</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0211-9809</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванова Анастасия Константиновна</p><p>198255 Санкт-Петербург, пр-кт Ветеранов, 56</p></bio><bio xml:lang="en"><p>Ivanova Anastasiya Konstantinovna</p><p>56 Veteranov Prospekt, Saint Petersburg 198255</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Варанкина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Varankina</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>198255 Санкт-Петербург, пр-кт Ветеранов, 56</p></bio><bio xml:lang="en"><p>56 Veteranov Prospekt, Saint Petersburg 198255</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коркина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Korkina</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>198255 Санкт-Петербург, пр-кт Ветеранов, 56</p></bio><bio xml:lang="en"><p>56 Veteranov Prospekt, Saint Petersburg 198255</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рахимова</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rakhimova</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>197022 Санкт-Петербург, ул. Льва Толстого, 6-8</p></bio><bio xml:lang="en"><p>197022 Санкт-Петербург, ул. Аъеа Толстого, 6—8</p></bio><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Санкт-Петербургский государственный университет»; СПб ГБУЗ «Городской клинический онкологический Диспансер»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg State University; City Clinical Oncological Dispensary</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>СПб ГБУЗ «Городской клинический онкологический Диспансер»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Oncological Dispensary</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>СПб ГБУЗ «Городской клинический онкологический Диспансер»; ГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И. Мечникова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Oncological Dispensary; I. I. Mechnikov North-West State Medical University, Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>СПб ГБУЗ «Городской клинический онкологический Диспансер»; ФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Oncological Dispensary; Academician I. P. Pavlov First St. Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Academician I. P. Pavlov First St. Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>18</day><month>12</month><year>2024</year></pub-date><volume>14</volume><issue>3</issue><fpage>49</fpage><lpage>55</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Орлова Р.В., Андросова А.В., Топузов Э.Э., Беляк Н.П., Кутукова С.И., Авраменко И.В., Иванова А.К., Варанкина А.А., Коркина А.А., Рахимова Г.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Орлова Р.В., Андросова А.В., Топузов Э.Э., Беляк Н.П., Кутукова С.И., Авраменко И.В., Иванова А.К., Варанкина А.А., Коркина А.А., Рахимова Г.А.</copyright-holder><copyright-holder xml:lang="en">Orlova R.V., Androsova A.V., Topuzov E.E., Belyak N.P., Kutukova S.I., Avramenko I.V., Ivanova A.K., Varankina A.A., Korkina A.A., Rakhimova G.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.malignanttumors.org/jour/article/view/1410">https://www.malignanttumors.org/jour/article/view/1410</self-uri><abstract><p>Ангиосаркома молочных желез представляет собой редкое злокачественное заболевание, которое составляет менее 0,5% от всех случаев рака молочной железы. Характеризуется заболевание быстрым ростом, агрессивным течением, активной диссеминацией процесса и плохим ответом на лечение. Особенность заболевания состоит в сложности диагностики процесса, поскольку клиническая картина не является специфической и зачастую протекает под маской кожных заболеваний, такие как экзема, атопический дерматит, розацеа и т. д. Ведущим звеном лечения данного заболевания является хиругическое лечение. В данной статье представлен собственный опыт ведения пациентов с ангиосаркомами молочных желез, возникших после лечения карциномы молочной железы в СПб ГБУЗ ГКОД.</p></abstract><trans-abstract xml:lang="en"><p>Breast angiosarcoma is a rare malignancy that accounts for less than 0.5% of all breast cancers. The disease is characterized by rapid growth, aggressive course, active dissemination of the process and poor response to treatment. The peculiarity of the disease lies in the complexity of diagnosing the process, since the clinical picture is not specific and often occurs under the guise of skin diseases such as eczema, atopic dermatitis, rosacea, etc. Also, the complexity of diagnosis is complemented by the lack of specific imaging methods, thanks to which it would be possible to diagnose angiosarcoma with high accuracy. The leading element of treatment is a combined approach, namely a combination of surgical excision, drug therapy and radiation. This article presents our own experience in managing a patient with angiosarcoma of the right breast, which arose 7 years after the treatment of breast carcinoma in the St. Petersburg City Clinical Oncology Center.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ангиосаркома</kwd><kwd>молочная железа</kwd><kwd>радиоиндуцированная ангиосаркома</kwd></kwd-group><kwd-group xml:lang="en"><kwd>angiosarcoma</kwd><kwd>breast</kwd><kwd>radiation inducedangiosarcoma</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Статья подготовлена без спонсорской поддержки</funding-statement><funding-statement xml:lang="en">The article was prepared without sponsorship</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Virgilio E., Lombardi M., Stefano D.D., et al. 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