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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">tumors</journal-id><journal-title-group><journal-title xml:lang="ru">Malignant tumours</journal-title><trans-title-group xml:lang="en"><trans-title>Malignant tumours</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2224-5057</issn><issn pub-type="epub">2587-6813</issn><publisher><publisher-name>Rosoncoweb</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18027/2224-5057-2024-14-3s1-14-18</article-id><article-id custom-type="elpub" pub-id-type="custom">tumors-1342</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Редкие опухоли. Метастатический рак носоглотки</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4879-2687</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Болотина</surname><given-names>Л. В.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лариса Владимировна Болотина</p><p>125284 Москва, 2-й Боткинский пр-д., 3</p></bio><email xlink:type="simple">lbolotina@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Московский научно-исследовательский онкологический институт им. П. А. Герцена — филиал ФГБУ «НМИЦ радиологии» Минздрава России</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>18</day><month>11</month><year>2024</year></pub-date><volume>14</volume><issue>3s1</issue><fpage>14</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Болотина Л.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Болотина Л.В.</copyright-holder><copyright-holder xml:lang="en">Болотина Л.В.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.malignanttumors.org/jour/article/view/1342">https://www.malignanttumors.org/jour/article/view/1342</self-uri><abstract><p>Рак носоглотки (РН) является уникальной патологией, для которой характерна специфическая эндемичность, половые и возрастные особенности распределения, а также высокая чувствительность к консервативным методам лечения. Одной из особенностей РН является высокая ассоциация с вирусом Эпштейна-Барр (ВЭБ), что определяет особенность функционирования сигнальных путей и высокую иммуногенность опухоли.</p><p>Статья посвящена анализу исследований химио-иммунотерапии в 1 линии лечения рецидивного / метастатического РН. </p></abstract><kwd-group xml:lang="ru"><kwd>рак носоглотки</kwd><kwd>вирус Эпштейна-Барр</kwd><kwd>химио-иммунотерапия</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bray F., Laversanne M., Sung H., et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2024;74(3):229–263. https://doi.org/10.3322/caac.21834</mixed-citation><mixed-citation xml:lang="en">Bray F., Laversanne M., Sung H., et al. 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