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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">tumors</journal-id><journal-title-group><journal-title xml:lang="ru">Malignant tumours</journal-title><trans-title-group xml:lang="en"><trans-title>Malignant tumours</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2224-5057</issn><issn pub-type="epub">2587-6813</issn><publisher><publisher-name>Rosoncoweb</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18027/2224-5057-2023-13-3-64-71</article-id><article-id custom-type="elpub" pub-id-type="custom">tumors-1170</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL NOTES</subject></subj-group></article-categories><title-group><article-title>Успешное хирургическое лечение герминогенной опухоли средостения на фоне химиорезистентности</article-title><trans-title-group xml:lang="en"><trans-title>Successful surgical treatment of chemoresistant mediastinal germ cell tumor</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хакимов</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Khakimov</surname><given-names>G.  A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Голиб А. Хакимов, д. м. н., профессор, заведующий кафедрой онкологии; директор; руководитель онкологического отделения клиники</p><p>Ташкент</p></bio><bio xml:lang="en"><p>Golib A. Khakimov, MD, PhD, DSc, professor, Head of the Department of Oncology, Pediatric Oncology; Director;  Head of Oncology Department</p><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хакимова</surname><given-names>Г. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Khakimova</surname><given-names>G.  G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гулноз Г. Хакимова, к. м. н., доцент кафедры детской онкологии; онколог-химиотерапевт</p><p>Ташкент</p></bio><bio xml:lang="en"><p>Gulnoz G. Khakimova, MD, PhD, Associate Professor of the Department of Pediatric Oncology; Medical Oncologist of Nano Medical Clinic</p><p>Tashkent</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ташкентский педиатрический медицинский институт; Ташкентский городской филиал Республиканского специализированного научно-практического центра онкологии&#13;
и радиологии; Nano Medical Clinic</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Tashkent Pediatric Medical Institute; Tashkent City Branch of the Republican Specialized Scientific and Practical Center of Oncology and Radiology; Nano Medical Clinic</institution><country>Uzbekistan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Ташкентский педиатрический медицинский институт; Nano Medical Clinic</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tashkent Pediatric Medical Institute; Nano Medical Clinic</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>09</day><month>11</month><year>2023</year></pub-date><volume>13</volume><issue>3</issue><fpage>64</fpage><lpage>71</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хакимов Г.А., Хакимова Г.Г., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Хакимов Г.А., Хакимова Г.Г.</copyright-holder><copyright-holder xml:lang="en">Khakimov G.A., Khakimova G.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.malignanttumors.org/jour/article/view/1170">https://www.malignanttumors.org/jour/article/view/1170</self-uri><abstract><p>Тератома средостения является редкой первичной локализацией герминогенной опухоли. Мы представляем случай успешного хирургического лечения 24‑летнего мужчины с гигантской незрелой тератомой средостения, осложненной выраженными кардиореспираторными расстройствами.</p></abstract><trans-abstract xml:lang="en"><p>Mediastinal teratoma is a rare germ cell tumor. The mediastinum is the most common extragonadal site. Malignant tumors of the mediastinum account for 4 % of all extragonadal tumors of the mediastinum. We present a case of successful surgical treatment of a 24‑year-old man with a gigantic immature mediastinal teratoma complicated by severe cardiorespiratory disorders.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>средостение</kwd><kwd>незрелая тератома</kwd></kwd-group><kwd-group xml:lang="en"><kwd>mediastinum</kwd><kwd>immature teratoma</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Давыдов М. И., Полоцкий Б. Е., Мачаладзе З. О. и др. 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