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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">tumors</journal-id><journal-title-group><journal-title xml:lang="ru">Malignant tumours</journal-title><trans-title-group xml:lang="en"><trans-title>Malignant tumours</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2224-5057</issn><issn pub-type="epub">2587-6813</issn><publisher><publisher-name>Rosoncoweb</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18027/2224-5057-2014-2-11-23</article-id><article-id custom-type="elpub" pub-id-type="custom">tumors-103</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL REPORTS</subject></subj-group></article-categories><title-group><article-title>ВТОРИЧНЫЕ ОПУХОЛИ ПОДЖЕЛУДОЧНОЙ ЖЕЛЕЗЫ: ОПИСАНИЕ  СЛУЧАЕВ И ОБЗОР  ЛИТЕРАТУРЫ</article-title><trans-title-group xml:lang="en"><trans-title>Secondary tumors of the pancreas: case reports and literature review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сетдикова</surname><given-names>Г. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Setdikova</surname><given-names>G. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Контактная информация: Сетдикова Галия Равилевна — к.м.н., врач патологоанатомического отделения ФГБУ ГНЦ Федеральный медицинский биофизический центр им. А. И. Бурназяна  ФМБА России</p></bio><email xlink:type="simple">info@oncoprogress.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Паклина</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Paklina</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Паклина Оксана Владимировна  — д.м.н.,  заведующая патологоанатомическим отделением Московской городской больницы им. С. П. Боткина</p></bio><email xlink:type="simple">info@oncoprogress.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ротин</surname><given-names>Д. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Rotin</surname><given-names>D. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ротин Даниил Леонидович — д.м.н.,  заведующий патологоанатомическим отделением Московского Клинического Научного Центра Департамента Здравоохранения г. Москвы</p><p> </p><p> </p></bio><email xlink:type="simple">info@oncoprogress.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Федеральный медицинский биофизический центр им. А. И. Бурназяна</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Московская городская больница им. С. П. Боткина</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>Московский клинический научный центр</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>21</day><month>05</month><year>2015</year></pub-date><volume>0</volume><issue>2</issue><fpage>11</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сетдикова Г.Р., Паклина О.В., Ротин Д.Л., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Сетдикова Г.Р., Паклина О.В., Ротин Д.Л.</copyright-holder><copyright-holder xml:lang="en">Setdikova G.R., Paklina O.V., Rotin D.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.malignanttumors.org/jour/article/view/103">https://www.malignanttumors.org/jour/article/view/103</self-uri><abstract><sec><title>Введение</title><p>Введение: метастазы в поджелудочную железу крайне редки и составляют 4,5% всех опухолей поджелудочной железы. Как правило протекают бессимптомно  и выявляются случайно. Наиболее частым раком, метастазирующим в поджелудочную железу, является почечно-клеточный рак, после него в убывающем порядке следуют колоректальный рак, меланома, саркома и рак легких. Прогноз жизни больных определяется гистогенезом первичной опухоли и распространенностью онкологического процесса.</p></sec><sec><title> Описание случаев</title><p> Описание случаев: в данной статье представлены случаи метастазов почечно-клеточного рака, рака толстой кишки, рака легкого и местнораспространенных поражений при раке желудка и лимфомы. </p></sec><sec><title>Вывод</title><p>Вывод: приведено 10 наблюдений вторичных опухолей поджелудочной железы, что составило 5,4% (10 из184) от всех исследованных опухолей железы за этот период. По типу распространения:  в 6-и случаях отмечено метастатическое поражение железы и 4-х случаях — локальная инвазия.  Важным в обследовании  подобных больных является проведение  дифференциального диагноза с первичной  опухолью поджелудочной железы,  поскольку лечебная  тактика может существенно отличаться. Трудно решить вопрос о выборе правильной тактики лечения больных с данными нозологическими формами, за счет их чрезвычайной редкости.</p></sec></abstract><trans-abstract xml:lang="en"><p>Introduction: Metastases in the pancreas are very rare and amount 4.5% of all tumors of the pancreas. As a rule such tumors don’t have any specific symptoms and are diagnosed spontaneously. The most frequent metastasizing to the pancreas tumor is renal cell carcinoma, then in descending order – colorectal cancer, melanoma, sarcoma and lung cancer. Prognosis is based on the histology of the primary tumor and the stage of the disease.Case reports: This article describes cases of metastases of renal cell carcinoma, colorectal cancer, lung cancer and locally advanced cases of gastric cancer and lymphoma.Conclusion: In this article 10 cases of secondary tumors of the pancreas are presented which amounts 5,4% (10 of 184)of all tumors of the pancreas during this period. In 6 cases metastases are found and in 4 cases – local invasion. It is very important to provide differential diagnosis with primary tumors of the pancreas because treatment strategy may differ significantly. It is difficult to choose right treatment strategy in patients with such diagnosis due to its rarity.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>вторичные опухоли</kwd><kwd>метастазы</kwd><kwd>поджелудочная железа</kwd></kwd-group><kwd-group xml:lang="en"><kwd>secondary tumors</kwd><kwd>metastases</kwd><kwd>pancreas</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Nakamura E., Shimizu M., Itoh T., et.al. Secondary tumors of the pancreas: clinicopathological study of 103 autopsy cases of Japanese patients. Pathol Int. 2001; 51: 686–90.</mixed-citation><mixed-citation xml:lang="en">Nakamura E., Shimizu M., Itoh T., et.al. Secondary tumors of the pancreas: clinicopathological study of 103 autopsy cases of Japanese patients. 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